P-glycoprotein

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P-glycoprotein

·September 7, 2012·2 min read

Strategy Developed to Improve Delivery of Medicines to the Brain

The experimental treatment method allows small therapeutic agents to safely cross the blood-brain barrier in laboratory rats by turning off P-glycoprotein, one of the main gatekeepers preventing medicinal drugs from reaching their intended targets in the brain.

Featured Neurology Neuroscience Open Neuroscience Articles

·June 16, 2021·6 min read

P-Glycoprotein Removes Alzheimer’s-Associated Toxin From the Brain

P-glycoprotein, a critical toxin pump in the body, has the ability to remove amyloid plaques from the brain. Researchers say increasing P-gp in the blood-brain barrier of those at risk for Alzheimer's could postpone or prevent the onset of the neurodegenerative disease.

The image shows an MRI brain scan of a person with ALS.

Featured Neurology

·December 17, 2014·4 min read

New Approach for Treating ALS

Researchers propose improvements to how well ALS therapeutics work.

Image shows brain sliced from the experiment.

Brain Cancer Featured Neurology Open Neuroscience Articles

·April 5, 2016·4 min read

Opening the Blood-Brain Barrier to Deliver Drugs For Brain Diseases

According to a new study, researchers have discovered a new way to open the blood-brain barrier. The findings have implications for delivering medications to treat brain diseases and cancers.

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