Oxytocin produced in the BNST increased stress-induced social anxiety behaviors in mice. The findings shed light on why oxytocin can sometimes provoke anti-social effects.
Breastfeeding mothers with higher levels of oxytocin show more enhanced positive recognition of adult faces. The findings shed light on how oxytocin may support both continued nurturing behaviors and affects general social cognition of other adults.
Levels of oxytocin were substantially lower in adults who experienced parental divorce as children compared to those whose families remained together.
Researchers investigate how the eyes play a critical role in emotional expression and finding a potential mate.
Researchers have uncovered a link between the Nlgn3 gene and the oxytocin signaling pathway in mouse models of ASD. Nlgn3 disrupts the oxytocin signaling pathway in neurons in the reward system, consequentially resulting in reduced social interactions in mice.
Early-life exposure to antibiotics may impact brain signaling pathways associated with social behavior and pain regulation. Young mice treated with antibiotics had reduced expression of receptors that mediate endorphin, oxytocin, and vasopressin signaling in the frontal cortex.
Oxytocin, the so-called "love hormone," could help to treat cognitive disorders, including Alzheimer's disease. Researchers demonstrated oxytocin reversed the effects of amyloid-beta on hippocampal LTP in mice. The findings suggest oxytocin could be used as a therapeutic for the treatment of Alzheimer's disease and other dementias.
Using optogenetics, researchers were able to manipulate oxytocin producing cells in a highly precise manner. They discovered oxytocin can amplify aggression as well as social friendliness.
Researchers have identified both genetic and neural mechanisms associated with romantic love and attachment. The maintenance of romantic love is not only associated with subcortical brain regions but also higher-order centers of the brain. The propensity to sustain romantic love appears to also be affected by genetic variability, specifically with genes associated with dopamine, vasopressin, and oxytocin.