Researchers find no evidence that long term or higher opioid use increases a person's risk of developing Alzheimer's disease.
A new study reports there could be a genetic risk for mental illness in those who are more likely to misuse drugs.
Rice University researchers detail the dynamics of how receptors alter their shapes to control sensitivity of the gate to chemical signals.
Blocking dorsal root ganglion pain neurons from releasing microRNA-21 has an anti-inflammatory effect at the cellular level, preventing neuropathic pain, researchers report.
Almost 1 in 5 people now use opioids to treat migraines. Researchers say a growing number of patients are using opioids to replace medications approved and specially designed to treat migraines, despite knowing the risks of opioid use.
A new study reports researchers have discovered a brain mechanism that could be a suitable target to prevent addiction and tolerance to opioids.
Study reveals 27.8% of pain medications with high abuse potential make it all the way through the development process, compared to only 4.7% of medications with lower potential for abuse.
Researchers have developed a new pain relieving medication that is as strong as morphine, but is less likely to be addictive, and with fewer side effects.
Researchers have developed a new pain killer that is on par with conventional opioids, but does not affect respiration, which is the main cause of opioid overdose.
A new vaccine blocks the effects of heroin by preventing the drug from crossing the blood-brain barrier. Researchers believe the vaccine could be helpful in curbing the opioid epidemic.
35% of patients who used ketamine to manage pain reported significant side effects ranging from hallucination, out-of-body experiences, visual disturbances, and urinary dysfunction. 20% of the side effects were linked directly to ketamine, and 15% associated with ketamine in combination with other drugs.
Opiate exposure causes synaptic rewiring in the nucleus accumbens in addition to decreasing dendritic spines. The findings shed light into the neurobiology of opiate relapse.
