Researchers are developing a monthly monoclonal antibody therapy for the treatment and management of chronic pain. The hope is this new therapy can replace opioids for pain management.
Researchers have developed a new compound that selectively targets the brain's analgesic circuitry, but does not trigger potentially lethal side effects like traditional opioids.
Researchers report a 41% increase in the prescription of opioids for small animals over the past 10 years. The study reports the increase could potentially provide human access to the drugs, fueling the opioid epidemic.
A newly developed experimental vaccine can diminish the fatal respiratory effects of carfentanil and fentanyl in rodent models.
Exposure to the opioid fentanyl induces autism-like behaviors in mice by activating mu-opioid receptors in the anterior cingulate cortex.
A newly developed vaccine blocks the ability of the opioid Fentanyl's ability to enter the brain, thus blocking the drug's "high".
According to a new report, long term use of opioid for pain can increase the risk of patients developing depression.
A new study clarifies the mechanism behind how ketamine works as an antidepressant. Researchers say there is evidence to suggest ketamine binds to NMDA receptors, instead of opioid receptors. Reducing the belief that ketamine is an opioid may make patients with depression more open to using the treatment.