Changes in functional connectivity within the fatigue network occur in response to cognitive fatigue.
Postural orthostatic tachycardia syndrome (POTS), a disorder characterized by sudden fainting, may be an autoimmune disease. A new study reveals 89% of patients with the condition had elevated levels of autoantibodies against the adrenergic alpha 1 receptor. The potential biomarker can be identified via blood samples.
In healthy older adults, depression and cortical amyloid may be associated with early changes in cognition. The findings provide an additional biomarker for Alzheimer's disease.
Estrogens were significantly elevated in fetuses that later went on to develop autism. Higher levels of prenatal estrogens were more predictive of ASD than higher levels of prenatal androgens. The study supports a twenty-year-old theory that increased prenatal sex steroid hormones are a potential cause of autism spectrum disorder.
Researchers implanted a genetic mutation that encodes the DAT protein from a child with ASD into mice. The mice began to exhibit autism-like behavioral deficits. Mice with the DAT T356M mutation had reduced social interaction and a loss in social dominance. The mice also demonstrated an increase in hyperactivity. At the physiological level, the researchers found impaired striatal dopamine transmission and clearance.
An asymmetric coupling between the peripheral visual and olfactory sensory systems allows for enhanced steering response to discrete objects in mosquitos.
Recently, the WHO declared vaccine hesitancy one of the top ten international public health problems. They report the crisis is man-made, unnecessary and dangerous. Researchers are calling on search engines and social media organizations to do more to stem anti-vaccine rhetoric, and stop the spread of disinformation surrounding vaccinations. They also call for governments to better support mandatory immunization programs.
Neuroimaging study reveals teens with more gray matter in the caudate nucleus and left cerebellum were at increased risk of problem alcohol use over time. The findings reinforce the idea that brain structure differences may contribute to both psychiatric and substance use disorders.
A newly developed vaccine for meningitis and other bloodstream infections caused by the meningococcal group B bacteria will allow for the immunization of younger children. The new vaccine also addresses several limitations of the current meningitis vaccine.
Anticholinergic drugs, commonly prescribed to treat a range of disorders, from Parkinson's disease to bladder conditions, may increase dementia risks. The increased risk was linked to anticholinergic antidepressants, antipsychotics, bladder control, epilepsy and Parkinson's disease medications. There were no increased risks associated with other types of anticholinergics, such as gastrointestinal drugs or antihistamines.
Learning a new skill may involve the generation of new neural activity patterns.