The protein beta-arrestin-2 increases tau tangle accumulation in Alzheimer's disease and frontotemporal dementia but interfering with the removal of excess tau from the brain.
Researchers report memantine, an FDA approved drug, may not only alleviate symptoms of mild Alzheimer's disease, but could also prevent progression of the disease if used before symptoms appear.
Researchers report exosomes help neuron-to-neuron growth and the transfer of oligomer amyloid beta, resulting in apoptosis. The study reveals exosomes may be a primary mediator of the pathogenic progression of Alzheimer's disease.
A new Journal of Neuroscience study reports elevated levels of BACE1, an enzyme associated with neuronal damage in Alzheimer's disease, were identified in postmortem brain samples of those with HIV.
Researchers reveal a compound in green tea extract may help protect the brain against cognitive decline associated with Alzheimer's by coating toxic oligomers.
A new paper details a technology that can detect pathological oligomeric forms of tau in Alzheimer's patients through human blood platelets.
Researchers have developed a new imaging technique that makes it possible to study why proteins associated with Alzheimer’s and Parkinson’s diseases may go from harmless to toxic.
A new study reports a computer simulation has been able to explore the initial steps of the molecular processes that lead to Alzheimer's disease.
Researchers made a subtle alteration to the amyloid beta protein. The change affect its aggregation behavior and stabilizes an intermediate form with enhanced toxicity.