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oligodendrocytes

Featured Genetics Neurology Neuroscience

·May 1, 2019·6 min read

A comprehensive map of how Alzheimer’s affects the brain

Axon myelination is significantly disrupted in patients with Alzheimer's disease. Researchers also found brain cells of men and women vary significantly in how their genes respond to the neurodegenerative disease.

Featured Genetics Neuroscience Psychology

·April 24, 2019·4 min read

Hypersociability in Williams syndrome result of Myelination deficits

Myelin thickness and oligodendrocytes were significantly reduced in the prefrontal cortex in mouse models of Williams syndrome.

Featured Neurology Neuroscience Open Neuroscience Articles

·April 18, 2019·5 min read

Study shows promise in repairing damaged myelin

A study in mouse models of multiple sclerosis demonstrates a compound called sobetirome promotes remyelination, and a derivative of the compound can penetrate the blood-brain barrier to enable a tenfold increase in infiltration to the CNS. Researchers are confident their research will translate from mice into humans, providing a new avenue of treatment for MS.

Brain Cancer Featured Genetics Neurology Neuroscience

·April 11, 2019·4 min read

Shutting down deadly pediatric brain cancer at its earliest moments

Dysregulation of Zfp36l1 causes neural lineage progenitor cells to grow rapidly, taking on the properties of fast growing stem cells as they become cancerous.

Featured Genetics Neurology Neuroscience

·January 29, 2019·5 min read

Researchers Generate and Track Development of Myelin Producing Brain Cells

Researchers have successfully created stem cell derived brain cells which can generate oligodendrocytes, neurons and astrocytes.

Featured Genetics Neurology Neuroscience

·January 23, 2019·5 min read

Shedding Light on Brain Cell Changes in Multiple Sclerosis

A new study sheds light on brain cells implicated in multiple sclerosis. Researchers found there are several types of oligodendrocytes, and the ratio of these cells differ significantly in those with MS. The findings could help develop new targeted treatments for progressive multiple sclerosis.

Featured Neurology Open Neuroscience Articles

·January 22, 2019·4 min read

Helping Cells to Help Themselves May Benefit Multiple Sclerosis

Researchers have discovered how the body is able to initiate repair mechanisms which can limit the extent of damage to the myelin sheath. The findings could help with the development of new therapies for multiple sclerosis.

Featured Neuroscience

·January 3, 2019·3 min read

New Insight Into the Process of New Neuron Generation in the Adult Brain

Researchers discover the protein nestin produced in astrocytes plays a role in inhibiting neural differentiation. The study reports nestin does not control adult neurogenesis by acting within neural stem cells, but by regulating Notch signals neural stem cells receive from astrocytes.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·December 18, 2018·4 min read

Study Reveals What May Prevent Remyelination

Study reveals PRRX1 gene expression results in cell cycle arrest and quiescence of oligodendrocyte progenitors, blocking myelin production.

Featured Neuroscience Open Neuroscience Articles

·December 4, 2018·5 min read

Improving Understanding of the Formation of New Neurons in the Mammalian Adult Brain

Researchers have developed an innovative approach to identifying novel cellular targets and pathways involved in wiring adult born neurons into existing brain circuits.