Neurons in the parafascicular thalamus project to three different parts of the basal ganglia. Targeting these circuits could be a new target for treating motor dysfunction and depression associated with Parkinson's disease.
Aggression toward members in an "outgroup" was associated with increased activity in areas of the brain associated with reward. Activity in the ventromedial prefrontal cortex impacted the level of aggression a person demonstrated against an outsider.
Researchers were able to predict, with 85 percent accuracy at the beginning of the study, which participants would go on to develop chronic pain based on the level of interaction between the frontal cortex and the nucleus accumbens.