Combining neuroimaging data with artificial intelligence, researchers have identified two distinct neuroanatomical subtypes of schizophrenia. The first, more typical subtype is associated with a lower widespread volume of gray matter compared to healthy controls. In the second subtype, gray matter volume is largely similar to healthy brains.
Researchers implanted pacemaker electrodes into the medial forebrain bundle of patients suffering from major depression and performed deep brain stimulation. In a matter of days, in six out of seven patients, symptoms such as anxiety, despondence, listlessness and joylessness had improved considerably.
Opioid withdrawal cuts off the supply of serotonin to the nucleus accumbens, dramatically reducing sociability in mice and increasing social aversion.
Researchers report sleep deprivation intensifies and prolongs pain.
Dopamine D2 receptor overexpression in cholinergic interneurons of the nucleus accumbens may explain why some are more prone to cocaine addiction than others.
A new study implicates serotonin neurons in the nucleus accumbens with social behavior in mouse models of ASD. When serotonin release was triggered, researchers noted social behaviors normalized.
A new study uses MRI technology to map the neuroanatomical differences and similarities in two different kinds of extroverts.
UCSF Gallo scientists show that drinking releases brain endorphins Drinking alcohol leads to the release of endorphins in areas of...
A neuroimaging study looks at how closely the human-pet relationship mirrors the mother-child bond.
Glucose takes longer to get into the nucleus accumbens of obesity-prone rat models. Researchers also discovered excess levels of glutamate in obesity-prone rats, implying a deficiency in the neurotransmitter recycling process normally maintained by astrocytes.
Iron levels in the basal ganglia steadily increase throughout development and, in two sub-regions, continue to increase into adulthood. Decreased levels of iron in the putamen was correlated with impaired cognitive performance involving reasoning and spatial processing. Findings suggest the brain requires iron for healthy cognitive development.
Targeting synaptic calcium permeable receptors in the nucleus accumbens and blocking them could delay or prevent the onset of Alzheimer's associated neuropsychiatric symptoms, and ultimately cognitive decline.