Reduced WAVE1 levels decreased preference for cocaine in mice, researchers report.
Study finds mice show sensitivity to two different types of regret, and the different thought processes stem from different parts of the brain. Researchers also identified a genetic marker that predisposes maladaptive stress response traits and vulnerability to depression was linked to sensitivity to one type of regret.
A new study implicates serotonin neurons in the nucleus accumbens with social behavior in mouse models of ASD. When serotonin release was triggered, researchers noted social behaviors normalized.
Cocaine and sucrose neuron ensembles in the nucleus accumbens are mostly non-overlapping.
Opiate exposure causes synaptic rewiring in the nucleus accumbens in addition to decreasing dendritic spines. The findings shed light into the neurobiology of opiate relapse.
Researchers implicate neurons within the dorsolateral septum in the regulation of fearful behaviors in mice.
The findings suggest that therapeutics targeting the path between two critical brain regions, the amygdala and the nucleus accumbens, represent...
Researchers explore the neuroscience behind binge eating and the triggers that might make us reach for comfort foods.
Blocking the release of dynorphin, researchers restore motivation in animals experiencing pain. The findings may help in the development of new, less addictive, pain medications.
A new study reports binge drinking affects gene expression in both males and females differently. In females who binge drink, genes linked to hormone signaling and immune function become altered, whereas in males, alterations occur to genes associated with nerve signaling.
Drug combination targets brain circuits in the nucleus accumbens and completely eliminate chronic pain behavior.
Researchers have identified a new reward system in the brain. The study found long-range GABA neurons from the ventral tegmental area to the ventral nucleus accumbens shell are engaged in reward and reinforcement behaviors. This GABAergic projection inhibits cholinergic interneurons.
