The findings suggest that therapeutics targeting the path between two critical brain regions, the amygdala and the nucleus accumbens, represent... Read More
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UCSF Gallo scientists show that drinking releases brain endorphins Drinking alcohol leads to the release of endorphins in areas of... Read More
Researchers were able to predict, with 85 percent accuracy at the beginning of the study, which participants would go on to develop chronic pain based on the level of interaction between the frontal cortex and the nucleus accumbens. Read More
Scientists have laid bare a novel molecular mechanism responsible for the major depression symptom, anhedonia, the loss of the ability to experience pleasure. The brain circuit involved in this newly elucidated pathway is largely identical between rodents and humans, upping the odds that the findings point toward new therapies for depression and other disorders. Additionally, opinion leaders hailed the study’s inventive methodology, saying it may offer a much sounder approach to testing new antidepressants. Read More
Researchers discovered cocaine causes cells within the nucleus accumbens to boost the production of two specific proteins linked to addition and learning. Understanding addiction on a molecular level could lead to future developments for new treatments. Read More
Researchers implanted pacemaker electrodes into the medial forebrain bundle of patients suffering from major depression and performed deep brain stimulation. In a matter of days, in six out of seven patients, symptoms such as anxiety, despondence, listlessness and joylessness had improved considerably. Read More
Targeting the nucleus accumbens by using deep brain stimulation could modify specific eating behaviors linked to weight changes and obesity, a new study suggests. Read More
Using neuroimaging technology, researchers note increased activity in areas of the brain associated with empathy in subjects who underwent compassion training. Read More
A new study shows that the GLT1 protein plays a critical role in the craving for cocaine which develops after only a few days of cocaine use. However, exposure to ceftriaxone, an antibiotic used to treat meningitis, decreases cocaine cravings. Read More
Researchers identify circuitry in the brain which drives compulsive drinking in rats, and likely plays a similar role in humans. Read More
Brain structure abnormalities could predispose people to chronic pain following a lower back injury, researchers suggest. Read More
Researchers suggest a method of biologically manipulating neural circuitry could lead to a new pharmacological approach which could weaken cocaine withdrawal. Read More
