According to a new mathematical model of seizures, only the conductivity of the AMPA receptors in neurons in the temporal lobe significantly change, leading to stronger excitation and synaptic signals.
Researchers discover a protein switch which can increase or decrease memory building, depending on the signal it detects.
Researchers obtain new results which are likely to advance efforts to develop new drugs targeting NMDA receptors in the brain.
NMDA receptor hypofunction is involved in the reduction of sleep spindles and delta oscillations, which appear in the brain during deep natural sleep. Findings confirm the role NMDA receptors play in sleep disorders that accompany psychotic states.
Researchers have developed a new imaging agent, which uses PET scans to target receptors neurons implicated in memory and learning.
A single shot of ketamine administered to heavy drinkers following reactivation of their drinking memories led to a rapid decrease in the urge to drink. The effect lasted for over nine months.
Researchers report relatively simple math logic underlies complex brain computations.
According to a new study, postmortem brain tissue from females who suffered from depression had abnormally high expression levels of a number of genes which regulate the glutamate system.
A new study reports on a new drug target that has the potential to increase social interaction in some forms of ASD.
In a promising finding for epileptic patients suffering from persistent seizures known as status epilepticus, researchers reported today that new medication could help halt these devastating seizures.
A new study reports that both in solution and on supported membrane bilayers, multivalent interaction networks formed by major excitatory postsynaptic density scaffold proteins led to formation of PSD-like assemblies via phase separation.