Researchers have developed a light-sensitive switch that regulates a protein implicated in synaptic plasticity. The researchers believe the photoswitch could help shed light on learning, memory and neurodegeneration.
According to researchers, lithium, a drug commonly used to treat bipolar disorder, and rapamycin can help to protect neurons from further damage in those with TBI.
A new study reports long term memories might not be stored in synapses, as was previously thought.
Researchers reveal the structures of a portion of the NMDA receptor.
A new study reports microglia can diminish the adverse changes to neural circuitry bought on by chronic cocaine use.
Researchers have identified a mechanism which triggers the disruption in the brain's communication channels that occurs in schizophrenia.
In response to injury, microglia cross the spinal boundary from the central nervous system to the peripheral nervous system. While in the PNS, microglia provide the function of clearing cellular debris at the point of injury, then return to the CNS in an altered state. Researchers propose this could account for some damage associated with neurodegenerative diseases.
Researchers have built a mathematical model that describes the molecular events associated with the beginning stage of learning and memory formation in the human brain.
NYX-783, a newly discovered drug, helps modulate NMDA receptor function in neurons. The drug appears to be effective at suppressing the return of PTSD symptoms in rodent models.
CSHL structural biologists reveal molecular architecture of key NMDA receptor subunit Structure of GluN2D subunit when docked with certain neurotransmitters...
Bilirubin, a bile pigment most commonly associated with jaundice in newborns, appears to have neuroprotective properties. A new study in mice reveals bilirubin may protect the brain against oxidative stress.
Rice University researchers detail the dynamics of how receptors alter their shapes to control sensitivity of the gate to chemical signals.