Synaptic vesicles are a major source of energy consumption in inactive neurons, a new study reports.
The retrieval of mitochondria via a feedback loop is vital to sustaining synaptic transmission.
Tufts researchers have developed neurotransmitter-lipid hybrids that help transport therapeutic drugs and gene editing proteins across the blood-brain barrier in mice.
Dropping the level of the IL-33 immune molecule increased the number of synapses in the brain. In older mice, ramping up IL-33 helped push the number of new synapses toward a more youthful state.
Computational simulations reveal the integration of both neuronal and neurotransmitter systems at a whole-brain level is vital to fully understand the effects of psilocybin on brain activity.
Researchers have identified a novel neurotransmitter system in the brain. The system signals transmission of innate olfactory information to areas of the brain associated with emotional processing via the TAAR5 receptor. The findings could help in the development of new treatments for depression and schizophrenia.
Two activities support the brain's ability to establish reliable connections in the presence of significant biological background noise.
Study reveals how CD2AP may enhance Alzheimer's susceptibility. The gene affects neural communication by regulating the levels of regulatory proteins present around synapses.