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neuropharmacology

Featured Neurology Neuroscience Psychology

·October 2, 2024·4 min read

Cannabis Pill Reduces Agitation in Alzheimer’s Patients by 30%

A new study reveals that dronabinol, a synthetic form of THC, can reduce agitation in Alzheimer’s patients by 30%. Unlike current medications, dronabinol showed fewer side effects, such as delirium or seizures, making it a safer alternative.

Featured Neurology Neuroscience

·October 2, 2024·4 min read

Personalized Immune Therapy Offers Hope for MS Patients

A new study explores the use of tolerogenic dendritic cells (tolDCs) to restore immune balance in multiple sclerosis (MS) patients without compromising their immune system. The research reveals that MS patients’ immune cells have a pro-inflammatory signature, even after being modified for therapy.

Featured Neurology Neuroscience

·October 2, 2024·4 min read

Safer Epilepsy Treatment for Pregnant Women with Drug Combo

Rapamycin could counteract the harmful effects of Sodium Valproate, a common epilepsy medication, on fetal spinal cord development. Sodium Valproate is widely prescribed but poses risks during pregnancy, causing spinal malformations in fetuses.

Featured Genetics Neuroscience

·September 26, 2024·5 min read

Gut Microbiome and Aspirin May Reverse Hormonal Issues

Researchers found that mutations in the Sox3 gene cause hypopituitarism, a condition where the pituitary gland produces insufficient hormones, leading to growth issues and infertility. In a study on mice, they discovered that Sox3 mutations affect brain cells called NG2 glia, which are essential for hormone production.

Featured Neurology Neuroscience

·September 25, 2024·3 min read

Alzheimer’s Drug Faces Scrutiny Over Safety, Efficacy Concerns

The FDA-approved Alzheimer’s drug donanemab is under scrutiny due to concerns about its effectiveness and safety, according to an investigation. The study highlights multiple patient deaths during trials, design flaws, and the financial ties of panelists who recommended the drug's approval.

This shows researchers standing around a computer monitor.

Featured Neuroscience

·September 25, 2024·7 min read

AI Revolutionizes Drug Discovery for Rare Diseases

AI tool has identified drug candidates for over 17,000 rare and untreated diseases, offering hope for millions of affected individuals. This tool, TxGNN, stands out as the first model developed specifically to repurpose existing drugs for neglected conditions. It predicts which drugs may work and potential side effects, providing new avenues for treatment. The AI model is free to use and aims to expedite therapeutic discoveries for patients in need.

Featured Neurology Neuroscience

·September 24, 2024·5 min read

Parkinson’s Drug Linked to Impaired Decision-Making

Pramipexole, a Parkinson’s disease (PD) drug, impairs decision-making by hyperactivating the brain’s external globus pallidus (GPe) region. This research uncovers how the medication, while effective for PD symptoms, can lead to risky behaviors like gambling.

Featured Neuroscience Pain

·September 24, 2024·3 min read

Dopamine Not Essential for Placebo Effect in Pain Relief

New research reveals that dopamine is not directly responsible for the formation of placebo analgesia, contrary to previous beliefs. In a study with 168 participants, altering dopamine levels did not affect positive treatment expectations or pain relief.

Brain Cancer Featured Neurology Neuroscience

·September 22, 2024·5 min read

Antidepressant May Help Fight Glioblastoma Brain Tumors

Researchers have discovered that the antidepressant vortioxetine effectively combats glioblastoma, a deadly brain tumor, in lab tests and in mice. This drug, already FDA-approved, crosses the blood-brain barrier and could potentially improve treatment for glioblastoma patients when combined with standard therapy.

Featured Neuroscience

·September 9, 2024·3 min read

How Propofol Disrupts Consciousness Pathways

Researchers have mapped how propofol, a widely used anesthetic, alters brain connectivity to induce unconsciousness. Using fMRI, they found that propofol disrupts connections in the thalamus, reducing complex information processing and limiting sensory integration.

Featured Neuroscience Psychology

·September 4, 2024·5 min read

No Link Found Between Ozempic and Suicide Risk

A new study has found no evidence that GLP-1 analogues, common diabetes drugs, increase the risk of suicide, self-harm, or related mental health issues. Researchers analyzed data from around 300,000 people treated with these medications and found no clear link between the drugs and mental health risks.

Featured Neurology Neuroscience

·September 4, 2024·4 min read

Drug Trial Offers Hope for Progressive Supranuclear Palsy

A new clinical trial will test three drugs concurrently to find treatments for progressive supranuclear palsy (PSP), a rare and fatal neurodegenerative disorder. The trial aims to slow the relentless progression of PSP, which currently has no cure.

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neuropharmacology

Cannabis Pill Reduces Agitation in Alzheimer’s Patients by 30%

Personalized Immune Therapy Offers Hope for MS Patients

Safer Epilepsy Treatment for Pregnant Women with Drug Combo

Gut Microbiome and Aspirin May Reverse Hormonal Issues

Alzheimer’s Drug Faces Scrutiny Over Safety, Efficacy Concerns

AI Revolutionizes Drug Discovery for Rare Diseases

Parkinson’s Drug Linked to Impaired Decision-Making

Dopamine Not Essential for Placebo Effect in Pain Relief

Antidepressant May Help Fight Glioblastoma Brain Tumors

How Propofol Disrupts Consciousness Pathways

No Link Found Between Ozempic and Suicide Risk

Drug Trial Offers Hope for Progressive Supranuclear Palsy

How Scientists Cracked the Ketamine Code for Depression

Brain Prioritizes “Sound Offsets” During Hearing Repair

Glucose Levels Signal the Growth of Myelin

Why Your Brain “Dreams” Even When You’re Awake

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