Using CRISPR gene editing technology, researchers target the Shank3 gene in monkey embryos. Research backs previous findings of the importance of the Shank3 gene for brain development and its role in autism.
Lancaster University researchers report a drug developed to treat diabetes shows promise in reversing memory loss associated with Alzheimer's in mouse models of the disease. The drug appears to have a neuroprotective effect, enhancing brain growth factors while reducing amyloid plaques, chronic inflammation and oxidative stress. The drug also slows down the rate of neuron loss.
Scientists have discovered that significantly more neurons are generated in the brains of older animals if the signaling molecule Dickkopf-1 is turned off. The results give rise to the question whether the function of Dickkopf-1 may be turned off using drugs to prevent age related cognitive decline.
Researchers have identified how neural stem cells remain relatively free of age related damage.
Researchers have identified a molecule that signals brain tissue to form new connections to compensate for damage following a stroke.
A new study of the hippocampus reveals immature, plastic neurons are present in significant numbers during the entire lifespan. The findings shed new light on neuroplasticity.
A study of the salamander brain has led researchers at Karolinska Institutet to discover a hitherto unknown function of the...
Awakening dormant stem cells could stimulate the growth of new neurons. The findings could have significant implications for the treatment of neurodegenerative diseases.
Study identifies 40 genes in mice that actively suppress axon regeneration in the central nervous system.
Hippocampal adult-born neurons are responsible for memory consolidation during REM sleep.
Fenofibrate, an FDA-approved drug commonly used to treat high cholesterol, activated support cells around sensory neurons in mouse models of spinal cord injury, helping them regrow twice as fast as a placebo.
Tandospirone, a drug commonly used to treat anxiety related disorders, has been shown to reverse neurogenesis deficits caused by heavy alcohol use, researchers report.
