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neurogenesis

·August 29, 2025·4 min read

Stem Cells Use Toggle Switch to Regenerate Neurons

Scientists have uncovered how stem cells in the olfactory system continually regenerate neurons responsible for our sense of smell. Using live zebrafish imaging, cell tracking, and single-cell RNA sequencing, researchers identified a bistable toggle switch that drives progenitor cells to commit to specific fates and self-organize into “cellular neighborhoods.”

Featured Genetics Neuroscience

·August 21, 2025·5 min read

Gene Blueprint of Neural Stem Cells in the Brain Identified

A new study has mapped the genetic blueprint of neural stem and progenitor cells (NPCs), the rare cells responsible for generating new neurons in the adult brain. Using a digital sorting algorithm and cross-species analysis, researchers identified 129 NPC-specific genes, 25 of which are already linked to neurological disorders and 15 that may explain previously unknown conditions.

Featured Neurology Neuroscience

·August 9, 2025·4 min read

Natural Compound Combo Restores Aging Brain Cells

Scientists have identified a natural compound combination that reverses aging-related brain cell decline and removes harmful Alzheimer’s-linked proteins. The treatment, combining nicotinamide (vitamin B3) and the green tea antioxidant epigallocatechin gallate, restores guanosine triphosphate (GTP) levels—critical for neuronal energy and protein cleanup.

This shows an older man on an exercise bike in a hospital. A nurse is at his side. On the cycle is a monitor with a brain game.

Featured Neurology Neuroscience

·August 3, 2025·7 min read

Cycling Boosts Brain Function in Parkinson’s Disease

A new study reveals that long-term adaptive cycling can measurably reshape brain signals in people with Parkinson’s Disease, offering clues into how exercise relieves motor symptoms. Researchers used deep brain stimulation (DBS) implants to track neural activity before and after 12 sessions of dynamic cycling.

Featured Neuroscience

·July 22, 2025·6 min read

Aging Clock Unveils Compounds That Rejuvenate Brain Cells

Scientists developed a computational “aging clock” that measures the biological age of brain cells and identifies compounds with rejuvenating potential. By analyzing gene activity from healthy and neurodegenerative brain tissue, they pinpointed 453 interventions predicted to reverse cellular aging.

Featured Neuroscience Visual Neuroscience

·July 21, 2025·6 min read

Youthful Blood Restores Aging Retina and Vision

Researchers demonstrated that systemic factors from young mice can rejuvenate the aging retina by alleviating cellular senescence and restoring function. Using heterochronic parabiosis and single-cell RNA sequencing, the study identified AdipoR1 and its downstream AMPK signaling as key drivers of retinal rejuvenation.

Featured Genetics Neuroscience

·July 5, 2025·4 min read

Human Brains Keep Making Memory Neurons in Adulthood

A groundbreaking study shows that the human hippocampus continues producing new neurons well into late adulthood. Researchers identified neural progenitor cells—the precursors to neurons—in adults up to 78 years old, confirming ongoing neurogenesis in the memory center of the brain.

Featured Genetics Neuroscience

·May 22, 2025·6 min read

CRISPR Delivers RNA to Repair Neurons Right Where It’s Needed

Researchers have developed a new CRISPR-based technology that transports RNA to exact locations within neurons, where it can trigger repair and regrowth—offering hope for treating neurological diseases and injuries. Unlike traditional CRISPR tools that edit DNA, this system repurposes CRISPR-Cas13 to act like a “mailman,” carrying RNA to damaged sites using built-in molecular zip codes.

Featured Neuroscience

·May 9, 2025·3 min read

Oxygen Boost Sparks Early Brain Growth

A new study reveals that raising oxygen tension during weeks four to six of brain organoid development significantly promotes neurogenesis, guided by the oxygen-binding protein neuroglobin. Using cerebral organoids and cutting-edge imaging, researchers monitored internal oxygen levels and linked their changes to key stages in early brain development.

Featured Genetics Neurology Neuroscience

·April 11, 2025·6 min read

Hidden Neural Stem Cells May Hold Key to Brain Regeneration

Scientists have identified a previously unknown type of neural stem cell (pNSC) that exists outside the brain and spinal cord, overturning decades of neuroscience dogma. These peripheral neural stem cells, discovered in tissues like the lung and tail of mice, share key properties with brain-derived neural stem cells, including the ability to self-renew and differentiate into neurons.

This shows an AI representation of stem cells.

Featured Genetics Neuroscience

·February 8, 2025·5 min read

Stem Cells in the Brain Use Childlike Signals to Trigger Regeneration

Scientists have discovered that neural stem cells (NSCs) receive constant feedback from their daughter cells, influencing whether they remain dormant or activate to form new neurons and glia. This parent-child relationship helps regulate brain regeneration and repair.

Featured Neurology Neuroscience

·January 7, 2025·4 min read

Unlocking Spinal Cord Regeneration: Astrocytes Lead the Way

Spinal cord injuries (SCI) are challenging to treat due to the limited regenerative capacity of the central nervous system. A new study reveals that while ependymal cells in the spinal cord show minimal repair potential, astrocytes can transdifferentiate into oligodendrocytes, aiding in remyelination.