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neurofibrillary tangles

Cultured cells are shown and described in the caption.

·January 29, 2013·5 min read

A Better Way to Culture Central Nervous Cells

A protein associated with neuron damage in Alzheimer's patients provides a superior scaffold for growing central nervous system cells in the lab.

The image shows neurofibrillary tangles associated with Alzheimer's.

Featured Neurology

·June 26, 2013·3 min read

Alzheimer’s Disease Mouse Models Point To A Potential Therapeutic Approach

Using well known mouse models, researchers demonstrate a potential new target to fight Alzheimer's and other neurodegenerative diseases.

Neurology Neuroscience Business

·July 19, 2012·2 min read

Anti-Tau Drug Improves Cognition, Decreases Tau Tangles in Alzheimer’s Disease Models

Penn Medicine research presented today at the 2012 Alzheimer's Association International Conference shows that an anti-tau treatment called epithilone D (EpoD) was effective in preventing and intervening the progress of Alzheimer's disease in animal models, improving neuron function and cognition, as well as decreasing tau pathology.

This shows the difference between a healthy brain and one of an alzheimer's patient.

Featured Neurology

·February 25, 2014·2 min read

Brain Cell Activity Regulates Alzheimer’s Protein

A new study reports that increased neural activity boosts tau levels in the brain.

This shows a connectome view of a human brain.

Featured Neurology Neuroscience

·April 8, 2026·10 min read

Brain’s Unique Wiring Determines How Alzheimer’s Spreads

A 10-year study proves that Alzheimer’s tau tangles spread via an individual's unique neural connections. The findings confirm that targeting tau as it travels between synapses could halt the disease's progression.

Featured Neurology Open Neuroscience Articles Psychology

·January 18, 2017·4 min read

Delirium Could Accelerate Dementia Related Mental Decline

A new study reports delirium can accelerate cognitive decline in people undergoing pathological changes associated with dementia.

Featured Neurology

·April 11, 2016·2 min read

Dysfunctional Endosomes Precede Hallmarks of Alzheimer’s Disease

Abnormalities are linked to axonal dysfunctions and neurodegeneration in Alzheimer's disease and Down syndrome, a new study reports.

Featured Neurology Psychology

·October 15, 2018·8 min read

Early Alzheimer’s Brain Pathology Linked to Psychiatric Symptoms

Researchers report the earliest signs of neurodegeneration associated with Alzheimer's disease are linked to some psychiatric symptoms, including anxiety, depression and sleep disturbances. The findings could lead to earlier diagnosis of Alzheimer's.

Image of a brain of an alzheimer's patient.

Featured Neurology Open Neuroscience Articles

·January 25, 2016·4 min read

Exposure to Environmental Toxin May Increase Risk of Alzheimer’s and Other Neurodegenerative Diseases

Chronic exposure to the environmental toxin BMAA may increase the risk for developing neurodegenerative diseases including Alzheimer's, Parkinson's and ALS.

Featured Neurology Open Neuroscience Articles

·June 21, 2017·5 min read

Extra Virgin Olive Oil Preserves Memory and Protects Brain Against Alzheimer’s

Extra virgin olive oil can reduce neuroinflammation and activates autophagy, helping to protect memories and stave off dementia, a new study reports.

The image shows a brain scan of a person with TBI.

Featured Neurology

·May 29, 2013·3 min read

From Trauma to Tau

Researchers discover traumatic brain injuries generate tau oligomers, a protein associated with Alzheimer's and other neurodegenerative diseases. The discovery could provide insight into lasting brain damage caused by TBI.

Featured Neurology Neuroscience

·November 4, 2017·4 min read

Here’s What We Think Alzheimer’s Does to the Brain

A new paper explores different findings about the development of Alzheimer's and considers how personalized treatments may help combat this complex disease.

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neurofibrillary tangles

A Better Way to Culture Central Nervous Cells

Alzheimer’s Disease Mouse Models Point To A Potential Therapeutic Approach

Anti-Tau Drug Improves Cognition, Decreases Tau Tangles in Alzheimer’s Disease Models

Brain Cell Activity Regulates Alzheimer’s Protein

Brain’s Unique Wiring Determines How Alzheimer’s Spreads

Delirium Could Accelerate Dementia Related Mental Decline

Dysfunctional Endosomes Precede Hallmarks of Alzheimer’s Disease

Early Alzheimer’s Brain Pathology Linked to Psychiatric Symptoms

Exposure to Environmental Toxin May Increase Risk of Alzheimer’s and Other Neurodegenerative Diseases

Extra Virgin Olive Oil Preserves Memory and Protects Brain Against Alzheimer’s

From Trauma to Tau

Here’s What We Think Alzheimer’s Does to the Brain

How Severe Illness During Pregnancy Alters Fetal Brain Development

Aging Brains Maintain Robust Language Networks Despite Cognitive Decline

Youth Protein TIMP2 Restores Immune Function in the Aging Brain

Shame, Stigma, and Culture Prevent Male Domestic Violence Survivors From Seeking Help

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