Researchers report of elevated alpha-synuclein levels detected on the skin of patients with Parkinson's disease. The findings could offer a new biomarker for the recognition of Parkinson's before the disease reaches advanced stage.
Researchers discover neuronal activity can stimulate tau release from healthy neurons in the absence of cell death. The study shows treatment of neurons with known biological signaling molecules increases the release of tau into the culture medium.
According to a new study, the most common genetic cause of Parkinson’s is not only responsible for the condition’s distinctive movement problems but may also affect vision.
Researchers suggest the overexpression of a protein called alpha-synuclein appears to disrupt vital recycling processes in neurons. The study may have major implications for more fully understanding the causes and mechanisms of Parkinson’s disease.
Researchers identify a protein trafficking defect within brain cells that may underlie common non-familial forms of Parkinson’s disease. The study implicates two genetic variants that disrupt protein sorting in neurons.
Researchers visualize the molecular changes in a critical cell death protein that force cells to die. Defects in cell death have been linked to the development of diseases such as cancer and neurodegenerative conditions.
Researchers examine mutations of the LRRK2 gene and R1441G, known as the Basque mutation, to better understand Parkinson's disease among patients in the Basque Country.
Researchers report that the protein Klotho plays an important role in the health of myelin, the insulating material allowing for the rapid communication between nerve cells. These findings may lead to new therapies for multiple sclerosis (MS) and Alzheimer's disease (AD).
A recent study indicates microRNAs may play a far more important role in memory formation than previously thought. The research suggests microRNA—miR-182 is involved in developing memory in the amgydala.
A new finding turns one of the basics of neurobiology on its head, demonstrating that it is possible to turn one type of already differentiated neuron into another within the brain.
With a new insight into a model of Parkinson’s disease, researchers have identified a novel target for mitigating some of the disease’s toll on the brain.