FeaturedNeurology·May 23, 2012·3 min readAntioxidant Urate Could Protect Against Parkinson’s DiseaseStudy supports urate protection against Parkinson’s disease, hints at novel mechanism In vitro study indicates urate protection extends beyond antioxidant...Read More
ElectrophysiologyFeatured·February 2, 2013·3 min readCaught in the Act: Researchers Capture Key Moments in Cell DeathResearchers visualize the molecular changes in a critical cell death protein that force cells to die. Defects in cell death have been linked to the development of diseases such as cancer and neurodegenerative conditions.Read More
FeaturedGenetics·September 16, 2013·5 min readDNA Damage May Cause ALSResearchers discover link between an inability for neurons to repair DNA and neurodegenerative diseases such as ALS.Read More
FeaturedNeurology·January 31, 2013·5 min readExamining the so-called Basque Mutation of Parkinson’sResearchers examine mutations of the LRRK2 gene and R1441G, known as the Basque mutation, to better understand Parkinson's disease among patients in the Basque Country.Read More
FeaturedNeurology·February 7, 2013·3 min readExcess Protein Linked to Development of Parkinson’s DiseaseResearchers suggest the overexpression of a protein called alpha-synuclein appears to disrupt vital recycling processes in neurons. The study may have major implications for more fully understanding the causes and mechanisms of Parkinson’s disease.Read More
Neuroscience·May 20, 2011·2 min readHigh Iron Or Copper Levels Block Brain-cell DNA RepairNo one knows the cause of most cases of Alzheimer's, Parkinson's and other neurodegenerative disorders. But researchers have found that certain factors are consistently associated with these debilitating conditions. One is DNA damage by reactive oxygen species, highly destructive molecules usually formed as a byproduct of cellular respiration. Another is the presence of excessive levels of copper and iron in regions of the brain associated with the particular disorder.Read More
FeaturedNeuroscience·February 15, 2013·2 min readNeuronal Activity Induces Tau Release from Healthy NeuronsResearchers discover neuronal activity can stimulate tau release from healthy neurons in the absence of cell death. The study shows treatment of neurons with known biological signaling molecules increases the release of tau into the culture medium.Read More
FeaturedNeuroscience·January 30, 2013·2 min readNew Drug Target Identified for Multiple Sclerosis and Alzheimer’s DiseaseResearchers report that the protein Klotho plays an important role in the health of myelin, the insulating material allowing for the rapid communication between nerve cells. These findings may lead to new therapies for multiple sclerosis (MS) and Alzheimer's disease (AD).Read More
FeaturedNeurology·October 2, 2012·2 min readNew Research Model to Aid Search for Degenerative Disease CuresEfforts to treat disorders like Lou Gehrig’s disease, Paget’s disease, inclusion body myopathy and dementia will receive a considerable boost from a new research model created by UC Irvine scientists.Read More
FeaturedNeurology·January 18, 2013·3 min readPenn Vet Study Reveals a Promising New Target for Parkinson’s Disease TherapiesWith a new insight into a model of Parkinson’s disease, researchers have identified a novel target for mitigating some of the disease’s toll on the brain.Read More
FeaturedGenetics·February 15, 2013·2 min readResearch Uncovers a Potential link Between Parkinson’s and Visual ProblemsAccording to a new study, the most common genetic cause of Parkinson’s is not only responsible for the condition’s distinctive movement problems but may also affect vision.Read More
FeaturedNeuroscience·January 21, 2013·3 min readResearchers Turn One Form of Neuron into Another in the BrainA new finding turns one of the basics of neurobiology on its head, demonstrating that it is possible to turn one type of already differentiated neuron into another within the brain.Read More