FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·February 20, 2021·4 min readHow a Longevity Gene Protects Brain Stem Cells From StressFOXO3, a gene linked to longevity in humans, protects neural stem cells from the negative effects of stress.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·February 11, 2021·3 min readWake-up Call for Neural Stem CellsThe brain enzyme Pr-set7 activates dormant neural stem cells.Read More
FeaturedGeneticsNeuroscience·August 13, 2020·4 min readBecoming a Nerve Cell: Timing Is of the EssenceMitochondria regulate how neural stem cells become neurons during brain development. The findings may help explain how humans developed larger brains during evolution and how mitochondrial defects lead to some neurodevelopmental disorders.Read More
FeaturedGeneticsNeurology·August 6, 2020·4 min readImplanted Neural Stem Cell Grafts Show Functionality in Spinal Cord InjuriesResearchers implanted specialized neural stem cell grafts directly into mice with spinal cord injuries. As the grafts grew, they integrated with and mimicked the animal's existing neural network.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·April 2, 2020·4 min readLifestyle changes could delay memory problems in old age, depending on our genesThe genes GRB10 and ABTB1 are influential in nutrient-sensing pathways and memory. Researchers say these genes may be the molecular links between diet, neural stem cell aging, and cognitive ability.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·March 18, 2020·6 min readNew technique ‘prints’ cells to create diverse biological environmentsResearchers have created a new technique that can rapidly "print' two-dimensional arrays of cells and proteins that mimic a variety of cellular environments in the body.Read More
FeaturedNeuroscience·March 10, 2020·3 min readNeuron ‘nursery’ in nose tissue could help correct smell lossThe olfactory epithelium may be a hub for neurogenesis.Read More
FeaturedNeuroscience·February 28, 2020·4 min readNewly identified cellular trash removal program helps create new neuronsVimentin, a cellular filament, helps neural stem cells to clear damaged and clumped proteins, assisting in neurogenesis.Read More
ElectrophysiologyFeaturedNeuroscienceOpen Neuroscience Articles·February 6, 2020·3 min readBrain tissue stiffness is crucial for neurogenesisResearchers define the proteome of neural stem cell niches and the entire set of expressed proteins. The findings shed light on key regulators of neurogenesis.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·August 29, 2019·3 min readSignal blocks stem cell division in the geriatric brainA gene regulated called Id4 appears to be a key component in controlling stem cell proliferation.Read More
FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience ArticlesPsychology·August 9, 2019·3 min readHow chronic stress causes brain damageChronic stress causes autophagy in adult hippocampal neural stem cells. This results in a decline of hippocampal neurogenesis. Cognitive deficits and mood disorders that arise as a result of chronic stress are a result of autophagic death of hippocampal neural stem cells.Read More
FeaturedGeneticsNeuroscience·June 21, 2019·3 min readDiscovery of the cell fate switch from neurons to astrocytes in the developing brainThe FGF signaling pathway is an important extracellular regulator in the fate of neural stem cells switching from neurons to astrocytes in the cerebral cortex.Read More