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Multiple Sclerosis

·June 16, 2025·5 min read

Mitochondrial Link to Cerebellar Decline in MS

A new study reveals that mitochondrial dysfunction plays a central role in the loss of Purkinje neurons in the cerebellum, contributing to motor impairments in people with multiple sclerosis (MS). Researchers found that inflammation and demyelination in the cerebellum disrupt the mitochondria—key cellular power sources—leading to energy loss, neuron damage, and ataxia.

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·June 6, 2025·6 min read

Study Links Gut Bacteria to MS Risk and Reveals Key Triggers

A new twin study has identified specific gut bacteria that may contribute to the development of multiple sclerosis (MS), the most common inflammatory disease of the central nervous system. By comparing identical twins where only one has MS, researchers reduced confounding genetic and environmental factors and pinpointed 51 bacterial taxa with different abundances.

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·May 21, 2025·6 min read

8-Minute MRI Scan Can Diagnose MS Without Lumbar Puncture

A groundbreaking study has shown that multiple sclerosis (MS) can now be accurately diagnosed with a specialized MRI scan, eliminating the need for invasive and often painful lumbar punctures. The scan, which takes just 8 minutes, detects brain lesions centered on veins—a hallmark of MS—using a technique called T2*-weighted MRI.

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·April 29, 2025·3 min read

New Biomarker Predicts MS Progression

Researchers have identified a new biomarker in multiple sclerosis (MS): the thickness of the inflammatory rim surrounding brain lesions predicts how quickly and severely the disease progresses. By combining PET imaging and post-mortem brain analysis, the study showed that thicker rims lead to more aggressive brain damage.

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·April 29, 2025·4 min read

AI Model Detects MS Progression Earlier

A new AI model can detect the transition from relapsing-remitting MS to secondary progressive MS much earlier than traditional clinical diagnosis. Using data from over 22,000 patients, the model analyzes routine healthcare information and even indicates its confidence level for each assessment.

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·April 18, 2025·5 min read

Disrupted Myelin Protein Implicated in Schizophrenia

A new study has identified the protein hnRNP A1 as a key player in the production and maintenance of myelin, the fatty sheath that insulates nerve fibers in the brain. Myelin loss is common in disorders like multiple sclerosis and schizophrenia, and this research shows that hnRNP A1 disruptions can impair myelination at the molecular level, even before behavioral symptoms appear.

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·April 8, 2025·6 min read

AI Tool Tracks MS Brain Changes in Seconds

A new AI tool, MindGlide, can rapidly analyze routine brain MRI scans to detect subtle changes caused by multiple sclerosis (MS), such as brain shrinkage and lesions. Traditionally requiring expert interpretation, this process now takes just seconds, allowing more efficient monitoring of disease progression and treatment effects.

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·March 11, 2025·5 min read

How a Common Virus Triggers Brain Attacks in Multiple Sclerosis

New research highlights a critical link between antibodies produced against Epstein-Barr virus (EBV) and the development of multiple sclerosis (MS). Scientists discovered that these viral antibodies mistakenly target a protein called GlialCAM in the brain, triggering autoimmune responses associated with MS.

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·February 27, 2025·7 min read

Brain Map Reveals Early Signs of MS Before Symptoms Appear

Researchers have created a four-dimensional brain map that reveals how MS-like lesions form, providing new insights into the earliest stages of the disease. Using a marmoset model instead of mice, they tracked lesion development in real time with MRI imaging, identifying vulnerable brain regions weeks before visible damage occurred.

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·November 18, 2024·4 min read

Repurposed Multiple Sclerosis Drug May Improve Memory

Fampridine, used for improving walking in multiple sclerosis, may also enhance working memory in individuals with schizophrenia or depression. A study found that the drug significantly improved working memory in participants with initially poor performance, but had no effect on those with strong baseline memory.

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·November 4, 2024·4 min read

Keto Diet May Ease Multiple Sclerosis Symptoms

New research suggests the ketogenic diet could help manage multiple sclerosis (MS) by promoting the production of beneficial compounds in the gut. In a study, mice on a keto diet produced the ketone body β-hydroxybutyrate (βHB), which worked with gut bacteria to create immune-modulating metabolites.

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·November 3, 2024·8 min read

Researchers Create Cell-Level Wearable Devices to Restore Neuron Function

Researchers have developed tiny, wireless devices capable of wrapping around individual neurons, potentially aiding in the treatment of neurological disorders like multiple sclerosis. These devices, made from a soft polymer, roll up snugly around cell structures when exposed to light, allowing precise measurement and modulation of cellular activity. As they’re battery-free and actuated noninvasively by light, thousands of them could be deployed in the body simultaneously.