FeaturedNeuroscienceOpen Neuroscience Articles·April 19, 2022·4 min readExploring the Surprising Role of Motor System NeuronsMotor system neurons not only control movement, they also incite action.Read More
FeaturedNeurologyNeuroscience·February 3, 2023·3 min readFeatures That May Make Motor Neurons Vulnerable to ALSStudy links motor neurons' large cell size and supporting structures with genes that underly vulnerability to degeneration associated with ALS.Read More
FeaturedNeuroscience·March 9, 2016·3 min readFetal Motor Neuron Imbalance Can Hard Wire Later ProblemsFindings could lead to better understanding of neurodevelopmental and neurological disorders, such as autism and epilepsy.Read More
FeaturedGeneticsNeurologyOpen Neuroscience Articles·December 20, 2017·6 min readFirst Step Toward CRISPR Cure For ALSUC Berkeley researchers report they have successfully used CRISPR-Cas9 gene editing to delay symptoms and extend lifespan in mouse models of ALS.Read More
FeaturedNeuroscience·August 6, 2015·3 min readFly Model of Motor Neuron Degeneration Allows for Study at Single Cell ResolutionResearchers have developed a new model to study neurodegenerative diseases which affect motor neurons, such as ALS.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·February 5, 2018·3 min readGene Network That Regulates Motor Neuron Formation During Embryonic Development IdentifiedResearchers have identified a gene network that regulates the development of motor neurons during embryonic development.Read More
FeaturedGeneticsNeurologyNeuroscience·March 27, 2020·6 min readGene that first slows, then accelerates, progression of ALS in mice identifiedThe TBK1 gene regulates the disease progression of ALS in mouse models of the neurodegenerative disease. Loss of the TBK1 gene in motor neurons increases SOD1 aggregation and accelerates the onset of the disease.Read More
FeaturedGeneticsNeurology·August 12, 2015·4 min readGenetic Mutation Leads Transport Defect in ALSResearchers have identified a transport defect in models of familial ALS which leads to the accumulation of damaged components.Read More
FeaturedGeneticsNeurologyOpen Neuroscience Articles·August 2, 2016·4 min readHow a Single Gene May Protect Against Causes of Neurodegenerative DiseasesResearchers provide new insights into the role of UBQLN2 in removing toxic protein clumps.Read More
FeaturedGeneticsNeurologyNeuroscience·April 7, 2019·5 min readHow ALS progresses on genetic and cellular level revealed by high-res spinal cord studyChanges in gene expression help researchers identify ALS associated pathways and establish the key drivers of motor neuron degeneration in the disease.Read More
FeaturedNeuroscience·March 3, 2016·7 min readHow Many Neuron Types Are There in the Brain?Researchers devise a new approach to systematically identifying individual classes of neurons in the spinal cord.Read More
ElectrophysiologyFeaturedNeuroscience·February 17, 2021·6 min readHow Some Neurons Compensate for Death of Their NeighborsSome neurons have the ability to detect and compensate for neighboring neurons, while others do not. The findings shed new light on synaptic plasticity.Read More
