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motor neurons

·September 11, 2017·4 min read

Body’s Own Defense Against ALS Actually Drives Disease Progression at Later Stages

In early stages of ALS, autophagy helps to suppress disease progression, but accelerates the spread as the disease enters into later stages, researchers report.

Image shows an oligodendrocyte stained green.

Featured Neurology

·September 27, 2016·3 min read

Oligodendrocytes Induce Motor Neuron Death in ALS

A new study reports oligodendrocytes induce motor neuron death in ALS.

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Featured Neurology Neuroscience

·March 10, 2022·4 min read

Motor Neuron Toxin Associated With ALS Identified

PolyP, an inorganic polyphosphate released by astrocytes in people with ALS and frontotemporal dementia contributes to the signature motor neuron death associated with the disease pathologies.

Electrophysiology Featured Neuroscience

·May 2, 2014·3 min read

Researchers Reveal Circuitry of Fundamental Motor Circuit

Researchers have discovered the developmental source of a key type of neuron that allows animals to walk.

Featured Neurology Neuroscience

·May 11, 2020·3 min read

Resilience to ALS due to synaptic safety mechanism

Study reveals a self-corrective mechanism within synapses that is activated by neurodegeneration and slows disease progression in animal models of ALS.

Featured Genetics Neurology

·August 12, 2015·4 min read

Genetic Mutation Leads Transport Defect in ALS

Researchers have identified a transport defect in models of familial ALS which leads to the accumulation of damaged components.

Featured Neuroscience

·March 3, 2016·7 min read

How Many Neuron Types Are There in the Brain?

Researchers devise a new approach to systematically identifying individual classes of neurons in the spinal cord.

A graphic of two rats with white lights sparking between their heads is shown to depict the BTBI activity.

Electrophysiology Featured Neuroscience Open Neuroscience Articles

·February 28, 2013·6 min read

Brain-to-Brain Interface Allows Transmission of Tactile and Motor Information Between Rats 1000s of Miles Apart

Researchers electronically linked the brains of pairs of rats for the first time, enabling them to communicate directly to solve simple behavioral puzzles. A further test of this work successfully linked the brains of two animals thousands of miles apart - one in Durham, N.C., and one in Natal, Brazil.

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Electrophysiology Featured Neuroscience

·February 17, 2021·6 min read

How Some Neurons Compensate for Death of Their Neighbors

Some neurons have the ability to detect and compensate for neighboring neurons, while others do not. The findings shed new light on synaptic plasticity.

Featured Neurology

·March 19, 2018·4 min read

Paraplegic Rat Walks Again After Therapy, and Now We Know Why

Using electrochemical stimulation and robot assisted rehabilitation techniques, researchers restore walking ability in a paraplegic rat. The study reports reorganization of neural branching in the reticular formation leads to new connections and is key to motor skill recovery.

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