Mice lacking the autism-associated SHANK3 gene were more sensitive to sensation, including touch. The mice also had overactive excitatory neurons in the somatosensory cortex, which may account for sensory hypersensitivity.
People's opinions of political figures influence how plausible they believe the information they provide to be, even when the information is incorrect, a new study reports.
Using CRISPR gene editing, researchers introduce the SHANK3 gene variant into macaque monkeys. SHANK3 has previously been linked to autism in humans. The monkeys with the SHANK3 mutations exhibited behavioral traits and brain activity patterns similar to those seen in humans on the autism spectrum, Researchers hope the new model will facilitate new avenues of research for ASD.
Researchers report chronic stress can influence how we make decisions. In a new study, mice who were affected by chronic stress were more likely to make more risky decisions with higher payoff options than those who were less stressed.
Researchers reveal people react more to individual prices, but rational inattention leads to perception and overestimation of inflation rates.
Microglia that express the Alzheimer's associated APOE4 genetic variant are unable to effectively metabolize lipids. This causes lipids to build up, promoting inflammation and preventing effective neurotransmission.
A simple act such as rubbing your temples when you have a headache can help to alleviate pain. Researchers say this is because pain-responsive neurons in the brain quiet down when these neurons also receive touch input.