Brain organoids, or mini-brains, created from human stem cells appear to develop in much the same way as a human brain. The organoids follow an internal clock that guides their maturation in sync with the timeline for human brain development.
Researchers have developed a new device that can record, sense, and manipulate brain organoids. The device will allow researchers to make groundbreaking discoveries about how the brain develops and identify mechanisms of recovery following trauma.
Using brain organoid models, researchers have identified how the brain grows much larger and has three times as many neurons, as the brains of chimpanzees and gorillas.
Researchers recreated the damage seen in frontotemporal dementia in brain organoid models. The study reveals an experimental drug designed to treat Crohn's disease may help prevent neuron death associated with FTD.
Researchers have developed a new brain organoid model to study the mechanistic causes of Alzheimer's disease and test dementia drugs currently in development.
Newly developed brain organoids grown from stem cells showed organized waves of neural activity similar to that seen in living human brains.
Brain organoids can be used to study molecular mechanisms that drive brain aging and neurodegenerative disorders. The mini-brains allow for the testing of molecules that could become potential therapeutic treatment options for neurodegenerative diseases.
Brain organoid study reveals multiple changes in brain cells during early embryonic development may contribute to schizophrenia later in life.
