Astrocytes, not microglia, are responsible for constantly eliminating unnecessary and excessive adult synaptic connections in response to brain activity.
Study identifies a pathway involving astrocytes that help explain why some with multiple sclerosis experience seizures.
Recovery from multiple sclerosis-like symptoms in mice depends upon the ability for microglia to break down the remains of damaged cells.
Researchers have identified a bio-chemical circuit that supports neuron-microglia communication. When neurons are active, they release ATP. Microglia sense extracellular ATP and the compound draws the immune cell toward the neuron.
Study identifies a specific type of immune cell that induces inflammation in herpes simplex virus (HSV) encephalitis.
Researchers have devised techniques that allowed them to successfully replace dysfunctional microglia.
Microglia keep the Toxoplasma gondii parasite in check in the brain. Microglia release an immune molecule that recruit immune cells from the blood to control the parasite.