Experimental fecal transplant may help to improve autism symptoms, a new study reports.
Arizona State University researchers claim microbiota transfer therapy reduces symptoms associated with autism and gastrointestinal problems for two years post-treatment. The study suggests MTT may be a promising option for helping to treat children with ASD who also have GI problems. The researchers stress further research, including double-blind, placebo-controlled randomized trials with a larger cohort be carried out.
The mode of delivery at birth is a significant factor in the composition of gut bacteria. Children born via cesarean section have reduced levels of 'good' bacteria and an increased number of pathogens linked to the hospital environment.
Researchers have developed a probiotic 'cocktail' from gut bacteria found in infant feces. They say the 'cocktail' could help to increase the body's ability to produce short chain fatty acids. The probiotic could be used to help those suffering from cancers, autoimmune disorders, obesity, diabetes and other disorders which limit the ability of the body to produce SCFAs naturally.
A metabolite produced by lactic acid bacteria binds to the third hydroxycarboxylic acid receptor (HCA), signalling the immune system. Researchers believe the receptor evolved to allow great apes to consume foods that were starting to decay. They suggest the receptor could mediate some beneficial and anti-inflammatory effects of lactic acid in humans, and could serve as a target to treat inflammatory diseases.
Sensory neurons that send signals from the intestines to the brain stem extend to the interface of areas of the intestine that are exposed to high levels of microbial compounds. Turning off the neurons, researchers observed activated neurons in the brainstem as well as activation of gut neurons that control intestinal motility. The findings shed light on the potential mechanisms behind neurological abnormalities and intestinal diseases, including IBS.
A new study reports eating processed meats could contribute to mania associated with bipolar disorder. Researchers found people who had been hospitalized for mania were 3.5 times more likely to have eaten cured meats prior to admittance.
Researchers found significant differences in samples from the appendix of people with Parkinson's disease, specifically in microbial composition correlating with higher levels of toxic bile acids.
Researchers report bile acids play a key role in providing positive metabolic effects after weight loss surgery. The study also suggest the intestinal microbiome participates in post surgical improvements following gastric bypass. The findings could help develop new treatments for diabetes and obesity, researchers report.