A synthetic version of a fibupeptide, which is naturally produced by the microbiome, may help in the fight against antibiotic-resistant bacteria. Lugdunin has been shown to be effective against MRSA. The findings could help in the creation of a new class of antibiotics to treat infections currently resistant to drugs on the market.
Study reports specific gut bacteria can influence the development of Alzheimer's disease. In mouse models, long term antibiotic treatment reduced inflammation and the formation of amyloid plaques. However, the reduction was only seen in males. Additionally, the antibiotic treatment altered the activation of microglia in the male mouse models.
A new study reveals antibiotics given to pregnant women with Group B Streptococcus during labor can affect a baby's development of gut bacteria.
Researchers have identified an association between antibiotics administered to children aged two and under, and an increased risk of ongoing conditions ranging from ADHD to obesity. Children exposed to numerous courses of antibiotics as toddlers were more likely to be diagnosed with continuous conditions later in childhood. The study speculates that while antibiotics may only have a transient effect on the developing microbiome, this may have an impact on long-term illness.
Early-life exposure to antibiotics could impact brain development in areas associated with emotional and cognitive function, a new study reports. Researchers found penicillin exposure in infant mice altered the microbiome and gene expression in key areas of the developing brain.
Researchers administered antibiotics to rats for two weeks, depleting their gut microbiome. They then administered oxycodone. Compared to rats given only the opioid, those given the antibiotics had profound changes in how their brains responded to the pain killers.
A new study reports long term use of antibiotics in mice decreased levels of amyloid plaques and activated inflammatory microglial cells.
A new meta-analysis study reports regulating intestinal microbiota is more than 50% effective at helping to reduce anxiety. Non-probiotic interventions were more effective than probiotic interventions at helping to relieve symptoms.
Over 60s with poor appetite were found to have less variety of gut bacteria than those with healthier appetites. Additionally, those with good appetites had more microbes associated with diets rich in fruits and vegetables.
A new study reports FDA approved artificial sweeteners and some sports supplements are toxic to digestive gut bacteria. Researchers say the consumption of artificial sweeteners can adversely affect gut microbial activity, causing a wide range of health issues from cancers to type-2 diabetes.
Researchers have successfully identified autism risk in young mice by examining their mother's microbiome during pregnancy. The study, which may offer the earliest detection of autism, could pave the way to developing preventative measures against forms of autism by altering the maternal diet and probiotic intake.