A new synthetic peptide has the potential to deliver medications through the blood brain barrier.
According to researchers, pediatric leukemia patients exposed to high levels of methotrexate are more likely to have problems with mental flexibility and other cognitive skills as long term survivors.
Schizophrenia may, in part, be caused by immune system dysfunction, a new study reports. Treatment with Methotrexate, a drug commonly prescribed for autoimmune disorders like R.A, produced positive effects against some prominent schizophrenia symptoms.
New abortion bans and restrictions could result in life-threatening consequences for women of childbearing age with epilepsy, multiple sclerosis, and migraine due to restrictions placed on their ability to access life-saving medications. Patients in states with strict abortion restrictions are reporting they are unable to access teratogenic drugs to treat their conditions, including methotrexate, as the medications can induce abortion.
Using gene editing to boost the production of SOD3 in the choroid plexus reduced oxidative damage to brain tissue and cerebral spinal fluid in mice exposed to methotrexate.