People with untreated depression have lower levels of mitochondrial proteins. For those who responded to the SSRI antidepressants, the proteins returned to a normal level, but showed no increase in those who did not respond to medication.
Does the thought of the impending holidays leave you feeling stressed out? Researchers provide hints and tips for reducing anxiety and stress over the holiday period.
An increased white blood cell count has been linked to increased depression polygenic scores. The findings highlight the importance of the immune system in the development and severity of depression.
Complex PTSD (c-PTSD) occurs as a result of exposure to repeated and prolonged trauma, and affects up to 7.3% of the population. Researchers discuss how c-PTSD differs from PTSD, and provide insight on how the disorder can be treated.
Hippocampal HCN channels are more highly expressed in people with major depressive disorder. Antidepressants that increase cAMP signaling interfere with TRIP8b's ability to bind to HCN channels, helping to restore cognitive ability in those with MDD.
Digital cognitive behavioral therapy designed to curb insomnia during pregnancy reduces postpartum depression, researchers report.
Chronic stress accelerates the body's epigenetic clock, however, those that can manage the effects of stress by strengthening their emotional regulation and self-control can slow the process.
People with schizophrenia struggle to manage low-level negative emotions as the negative emotions increase. Those with schizophrenia are less likely to employ coping strategies when stressed than those without the disorder, causing an escalation in their negative emotions.