Five recent research papers shed light on elusive G protein-coupled receptors. New techniques and insights used to solve the GPCR structures are discussed.
Using a two-photon microscope capable of peering deep within living tissue, researchers at the University of California, San Diego School of Medicine have found new evidence that alpha-synuclein protein build-up inside neurons causes them to not only become leaky, but also to misfire due to calcium fluxes.
Researchers have captured the structural dynamics of the mitochondrion using fluorescent probes. This mapping could provide insights into the underlying causes of neurodegeneration associated with mitochondrial malfunction.
Researchers have been able to establish the structure of the sodium-potassium pump.