Melatonin and its metabolites promote long-term memory and protect against cognitive decline in mice.
Melatonin produced in the lungs acts as a barrier defense against SARS-CoV-2, the virus that causes COVID-19, by blocking the expression of genes that encode proteins in cells acting as viral entry points.
People with myopia appear to have delayed circadian rhythms and lower production of melatonin in the brain compared to those without the visual problem.
In mice, natural melatonin is linked to a pre-hibernation state, allowing for a slower metabolism and survival when food is scarce or the temperature is too cold.