Researchers report a variation of the MTNR1A gene is linked to an increased risk of developing Alzheimer's disease in older people. The same gene has previously been implicated in reduced tolerance to shift work in the aging population.
A new study reports women who are in their third trimester of pregnancy during months with less day light are at an increased risk of developing postnatal depression.
Researchers have created new 3D maps of two melatonin receptors. The models can be used to help develop new treatments that not only improve sleep, but may also treat a variety of other conditions from diabetes to cancer.
A retrospective analysis finds a correlation between sleep disorders and a lack of essential vitamins and minerals.
Breast milk may help train the circadian clock in young babies. The hormonal composition of breast milk changes throughout the day, with cortisol levels being higher in the morning and melatonin levels being higher at night.
Research examines the myths and science behind how the amino acid tryptophan, associated with turkey, affects mood.
Chronobiologists warn changing to daylight savings can have serious effects on both brain and general health. The change in time during spring was linked to a 24% increase in severe cardiovascular events in women. Researchers also noted the sudden change in time alters circadian rhythms, reduces the production of natural melatonin, impacts cognitive function, and may also foster tumor growth.
Researchers identified molecules that can modulate circadian rhythms by binding to the MT1 melatonin receptor in the hypothalamus.
The chances of having asthma are three times higher in teenagers who go to bed late at night compared to those who sleep earlier. The risk of allergic rhinitis is two times higher for late sleepers. Researchers say they can not be certain that staying up late is a cause for asthma, however, they note melatonin is often out of sync in late sleepers, and that could be an influential factor in the allergic response.
Researchers identified a specific neural network that positively responds to melatonin following concussion in children. Results suggest melatonin may help compensate for normal brain function that has been interrupted due to injury caused by concussion and helps prevent sleep disturbances.
In worms, melatonin promotes sleep by activating the BK channel through the MT1 receptor.
Normal sleep in mice is reliant upon bacteria that help produce neurotransmitters, such as serotonin, in the gut.
