A new study reveals how interneurons emerge and diversify in the brain.
Researchers shed light on what might be going wrong in the regulation of genes that govern the brain’s connectivity.
Mutations in the alpha-synuclein gene can cause increased vulnerability to pesticides, which may lead to Parkinson's disease.
MEF2C, a gene critical for brain development and regulating circuit formation in the brain also plays a significant role in inner ear development. Mutations of MEF2C have previously been linked to ASD. Researchers found mice with only one copy of the MEF2C gene had reduced activity in the auditory nerve.
Mouse models with one good copy and one inactive copy of the MEF2C gene showed social deficits, hyperactivity, repetitive behaviors, and significant reductions in vocalization.
Researchers have identified 11 new genes which offer important new insights into the disease pathways associated with Alzheimer's disease.
