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medicine

·December 8, 2025·5 min read

PTSD Linked to Accelerated Brain Aging

A new study using advanced deep-learning brain age estimation shows that World Trade Center responders with PTSD exhibit signs of accelerated brain aging. Using BrainAgeNeXt, a model trained on more than 11,000 MRI scans, researchers found that responders with PTSD had “older” appearing brains than those without the disorder, especially among individuals with longer exposure at Ground Zero.

Featured Genetics Neurology Neuroscience

·December 6, 2025·7 min read

Blocking a Key Protein Greatly Reduces Alzheimer’s Damage

New findings show that removing Centaurin-α1, a protein elevated in Alzheimer’s disease, significantly reduces inflammation, plaque buildup, and cognitive deficits in a well-established mouse model. Eliminating this protein normalized several brain pathways, protected neural connections in the hippocampus, and improved spatial learning.

Featured Genetics Neuroscience

·December 5, 2025·5 min read

Astrocytes Found to Drive Key Brain Changes in Nicotine Addiction

New research shows that astrocytes play an active role in nicotine-induced brain changes, challenging the long-held neuron-centered view of addiction. Nicotine stimulates receptors on astrocytes, triggering signaling cascades that boost glutamine synthetase activity and amplify glutamate-related pathways.

This shows a person drinking from a plastic water bottle and a brain.

Featured Neurology Neuroscience

·December 5, 2025·6 min read

Microplastics Accelerate Alzheimer’s and Parkinson’s Damage

A new review highlights five major ways microplastics can harm the brain, raising concerns that they may worsen neurodegenerative diseases like Alzheimer’s and Parkinson’s. These tiny particles can trigger inflammation, disrupt the blood–brain barrier, generate oxidative stress, impair mitochondria, and damage neurons.

This shows a child and parent walking in a "forest" of DNA.

Featured Genetics Neurology Neuroscience

·December 4, 2025·7 min read

Mutation in Key Enzyme Triggers Ferroptosis and Childhood Dementia

Researchers have identified how a single mutation in the GPX4 enzyme causes neurons to undergo ferroptosis, leading to severe early-onset dementia. The study provides the first molecular evidence that ferroptosis can directly drive neurodegeneration in the human brain.

Brain Cancer Featured Neurology Neuroscience

·December 4, 2025·9 min read

Fungal Molecule Shows Promise Against Brain Cancer

For the first time, chemists have fully synthesized verticillin A, a notoriously complex fungal molecule with striking anticancer potential. The molecule’s fragile structure required a complete rethinking of its synthetic sequence, enabling researchers to not only recreate it but design more stable and potent derivatives.

This shows people standing in a spotlight.

Featured Neuroscience Psychology

·December 3, 2025·6 min read

Mental Illness Can Also Bring Strengths

Mental illness is typically defined by its challenges, but growing evidence shows it is also linked to surprising strengths. Certain psychological conditions are associated with enhanced creativity, social sensitivity, emotional awareness, and resilience.

This shows the outline of a head and people.

Featured Neuroscience Psychology

·December 3, 2025·5 min read

Cognitive Profiles in Schizophrenia Are Being Ignored

A major scientific review reveals a deep knowledge gap in how cognition is affected when schizophrenia and personality disorders occur together. Despite the high prevalence and severe outcomes tied to this dual diagnosis, only a small number of rigorous studies have ever examined cognitive functioning in this group.

This shows a brain and three supplement pills

Autism Featured Neuroscience

·December 2, 2025·8 min read

Supplement Mix Reverses Autism Traits

Researchers have made a major advance, discovering that a low-dose mixture of zinc, serine, and branch-chain amino acids (BCAAs) can successfully alleviate behavioral symptoms in three different mouse models of autism. This breakthrough lies in the synergy of the three common nutrients, which work together to restore normal neural communication and reduce hyperactivity in the brain's emotional center.

This shows an angry man, a crying woman and a brain.

Featured Neuroscience Psychology

·December 2, 2025·5 min read

Abuse Survivors Show Unique Injury Signatures Tied to Suicide Risk

A new study finds that victims of intimate partner violence who also experience suicidal thoughts or behaviors show distinct and severe injury patterns on medical imaging. These patients were far more likely to present at night in emergency settings and had dramatically higher rates of head, spinal, and deep internal injuries.

Featured Neurology Neuroscience

·December 2, 2025·6 min read

Obesity Speeds Alzheimer’s Biomarker by Up to 95 Percent

New longitudinal research shows that Alzheimer’s disease blood biomarkers rise up to 95 percent faster in people with obesity than in those without. While baseline tests initially appeared lower due to blood dilution, long-term tracking revealed a significantly accelerated buildup of neurodegeneration and amyloid pathology.

This shows an older woman getting a vaccine.

Neuroscience

·December 2, 2025·12 min read

Shingles Vaccine Linked to 20% Lower Dementia Risk

A large population analysis found that older adults who received the shingles vaccine were significantly less likely to develop dementia over the following seven years. The study exploited a rare age-based rollout policy that closely mimicked a randomized trial, allowing researchers to isolate the vaccine’s true effect.

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medicine

PTSD Linked to Accelerated Brain Aging

Blocking a Key Protein Greatly Reduces Alzheimer’s Damage

Astrocytes Found to Drive Key Brain Changes in Nicotine Addiction

Microplastics Accelerate Alzheimer’s and Parkinson’s Damage

Mutation in Key Enzyme Triggers Ferroptosis and Childhood Dementia

Fungal Molecule Shows Promise Against Brain Cancer

Mental Illness Can Also Bring Strengths

Cognitive Profiles in Schizophrenia Are Being Ignored

Supplement Mix Reverses Autism Traits

Abuse Survivors Show Unique Injury Signatures Tied to Suicide Risk

Obesity Speeds Alzheimer’s Biomarker by Up to 95 Percent

Shingles Vaccine Linked to 20% Lower Dementia Risk

Nicotine Withdrawal Makes Smokers More Sensitive to Pain

PTSD Linked to Accelerated Brain Aging

Brain Uses AI-Like Computations for Language

Extreme Heat Linked to Delays in Early Childhood Development

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