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MD Anderson Cancer Center

·May 21, 2023·6 min read

Engineered Virus and Immunotherapy: New Hope for Glioblastoma Brain Cancer Patients

A new study details the safe and promising use of an engineered oncolytic virus (DNX-2401) alongside immunotherapy in treating recurrent glioblastoma (GBM). Despite not meeting its primary efficacy endpoint, the study achieved a significant 12-month survival rate, exceeding the prespecified efficacy threshold.

Featured Genetics Neuroscience

·January 21, 2023·3 min read

Novel mRNA Delivery Method Induces Collagen Repair and Could Replace Fillers for Skin Wrinkles

A novel mRNA delivery method that uses extracellular vesicles initiates collagen replacement in photoaged skin. A single injection increased collagen production and reduced wrinkle formation in targeted areas for two months. Researchers say the new delivery method could be used to treat a number of disorders including ones associated with protein loss associated with aging and hereditary disorders where genes and proteins are missing.

This shows the outline of a head and brain

Brain Cancer Featured Neurology Neuroscience

·June 6, 2022·5 min read

How the Gut Microbiome Impacts Immunotherapy Response in Glioblastoma Brain Cancer

Researchers say the gut microbiome may be a viable targetable biomarker to improve immunotherapy responses in those with glioblastoma and a range of other cancers.

Brain Cancer Featured Genetics Neurology Neuroscience

·June 10, 2019·5 min read

Study finds macrophages’ pathway to nurture PTEN-deficient glioblastoma: Mouse study

PTEN deficiency drives an increased expression of LOX. LOX attracts macrophages which protect gliobastoma brain cancer cells and provide growth factor support for the tumor, a new mouse study reveals.