Maternal inflammation has been linked to a range of neurodevelopmental and psychiatric disorders in children, including autism and schizophrenia. A new mouse study reveals maternal responses and subsequent developmental disorders are based on the mother's immunoreactivity to infection.
A new study backs up existing evidence that maternal immune activation can impact brain development in children. Researchers report immune activation during pregnancy or soon after birth can cause alterations to brain networks associated with social behavior, resulting in autism-like symptoms in the offspring.
University of Otago researchers report children have an increased risk of developing cognitive deficits linked to schizophrenia if their mother's immune system was activated as a result of infection during pregnancy.
Females offspring whose mothers experienced maternal immune activation while pregnant displayed an array of behavioral abnormalities associated with schizophrenia.
According to a new mouse study, exposure to vitamin D during pregnancy may prevent autistic traits in offspring.
Researchers report abnormal development of the prefrontal cortex and maternal stress may lead to brain activity and cognitive impairments linked to psychiatric diseases such as Schizophrenia and bipolar disorder.
Immune system activation of the mother during pregnancy can disrupt neurodevelopment in her offspring, a new study shows.
Researchers investigate the effects of maternal immune activation on the developing brain.
Increased levels of epoxide hydrolase in the prefrontal cortex were found in the brains of young mice whose mothers had suffered infection during pregnancy. Inhibiting epoxide hydrolase reverses cognitive and social deficits associated with neurodevelopmental disorders, such as ASD.
According to researchers, maternal immune activation during pregnancy can disrupt the expression of genes and processes associated with Autism.
A new study confirms previous findings that link inflammation during pregnancy to altered brain development in children. Researchers have created a machine learning algorithm that can predict the long term neurodevelopmental impact of MIA.
MIT researchers report mothers who contract severe infections during pregnancy face higher autism risks in their children. However, ASD risks could be reduced by blocking the function of certain strains of bacteria found in the mother's gut.