Researchers have developed a new class of drugs that may be more precise at blocking the production of toxic forms of amyloid beta.
People with primary progressive aphasia who have difficulty producing complex words as a result of their condition, compensate by stringing together a sequence of simpler words to convey the idea they wish to express.
Active social connection is the strongest protective factor for depression, a new study reports. Additionally, reducing sedentary activities such as watching TV or taking a nap can also help lower depression risk.
Combining αGITR antibodies with ICBs resulted in stronger survival benefits in mouse models of human glioblastoma brain cancer.
In healthy older adults, depression and cortical amyloid may be associated with early changes in cognition. The findings provide an additional biomarker for Alzheimer's disease.
The dorsomedial prefrontal cortex plays a critical role in mapping out personal actions and outcomes as well as responding to the actions of others.
Researchers report some patients with long-COVID have lasting nerve damage that appears to be caused by infection-triggered immune dysfunction.
Structural brain asymmetries are greater in those who are most likely to develop dementia, a new study reports.
Irisin, a hormone secreted by muscles during exercise, improved cognitive function and lowered levels of inflammation in mouse models. The findings have implications for the development of treatments for Alzheimer's and other neurodegenerative diseases.
Researchers have identified silent, seizure like activity in the hippocampus of two patients with Alzheimer's disease. They believe the seizure activity could contribute to the cognitive symptoms associated with the disease.
Post-mortem studies of brain tissue from ALS patients reveal an abnormal form of tau is present in novel brain areas, and the tau interacts with DRP1. The tau appears to cause the brain cell's mitochondria to fragment and increase oxidative stress. Reducing tau reversed the effect, decreasing oxidative stress and mitochondrial fragmentation.
Findings could help in the development of treatments to prevent brain inflammation associated with Alzheimer's disease.
