Researchers report the CPG2 protein is significantly decreased in the brains of people with bipolar disorder and mutations in the SYNE1 gene undermines the expression of CPG2. The study shows how a set of genetic differences in those with bipolar disorder can lead to specific psychological dysfunction in synapses in the brain. The findings could help improve diagnosis of the disorder and help develop new treatments for BD.
A new study reports eating processed meats could contribute to mania associated with bipolar disorder. Researchers found people who had been hospitalized for mania were 3.5 times more likely to have eaten cured meats prior to admittance.
People with bipolar disorder who experience frequent manic episodes had faster cortical thinning, specifically in the prefrontal cortex than those who reported less frequent episodes of mania. Researchers also noted faster enlargement of the brain's ventricles and slower thinking of the parahippocampal and fusiform cortical regions in those who experienced more frequent mania.