Researchers have identified the role Klf9 plays in the brain's response to stress. The study reports elevated levels of the protein were discovered in the hippocampus of women with MDD who faced stressful events.
Researchers have developed a new computational model of major depressive disorder. The model reveals older memories, as well as short term memories, are affected by major depressive disorder. Researchers say how long the memory deficits go back depends on how long the depressive episode lasts.
A new mouse study reveals females have a three fold higher abundance of EP3, in addition to elevated levels of genes associated with major depressive disorder in the locus coeruleus.
For those with treatment resistant depression, a new study reports ECT may not only be the most effective treatment, but also the most cost effective.
According to researchers, 40% of people with treatment resistant depression who received rTMS no longer had suicidal thoughts following treatment.
Researchers report intermittent theta burst stimulation can help to alleviate the symptoms of major depressive disorder. 49% of patients who received the treatment reported a significant decrease in symptoms, with 32% reporting remission of depression.
Researchers have identified 44 genetic risk factors for major depressive disorder. 30 of the variants are newly discovered. The team reports the genetic basis for MDD is shared with other psychological disorders and all humans carry some of the genetic risk factors identified.
Stimulating the Ent circuit helped improve depressive behaviors in mouse models of major depressive disorder, researchers report.
A new Nature Communications study reveals 80 newly identified genes that may be linked to an increased risk of developing major depressive disorder.
Researchers discover genes associated with major depressive disorder are altered in opposite directions in males compared to females.
According to researchers, people who suffer from major depressive disorder may report feeling more negative emotions when recalling specific autobiographical memories.
A new mouse study discovers different networks of brain activity in animals more susceptible to developing depression following a stressful event.
