Neurofeedback training can alter guilt-related networks and improve self-esteem in those with major depressive disorder. Read More
Antidepressants for major depressive disorder reduce the aversive response triggered by exposure to the suffering of others. Findings suggest antidepressants may lead to impaired empathy of pain perception. Read More
Using neuroimaging technology, researchers have identified three different subtypes of depressive disorder, including one that seems to be untreatable by common SSRI antidepressants. Read More
Study reports that almost 30% of women and 17% of men experience major depressive disorder episodes over the course of their lives. Read More
According to a new study, postmortem brain tissue from females who suffered from depression had abnormally high expression levels of a number of genes which regulate the glutamate system. Read More
A new study implicates serotonin 2c receptors with metabolic side effects caused by a common class of antipsychotic medications. Read More
During periods where personal choices of activities are constrained, natural mood regulation becomes impaired, resulting in an increased risk of depression. Read More
Only 45% of patients with major depressive disorder find benefit from cognitive behavioral therapy (CBT). A neuroimaging study reveals those who respond to CBT have greater neural activity in the right striatum and right amygdala pretreatment than those who find little benefit from the treatment. The findings could serve as a biomarker to discover who will respond to CBT. Read More
Exposure to everyday stressors may result in impairments in endothelial function for patients with major depressive disorder. The findings reveal a possible reason for the association between stress, depression and an increased risk of cardiovascular disease. Read More
A new study reports patients with major depressive disorder and treatment resistant depression have decreased levels of acetyl-L-carnitine in their blood. The findings could lead to new blood tests to diagnose the nature and severity of depression. Read More
Exposure to household pet dogs in the early years of life was associated with a significantly decreased risk of being diagnosed with schizophrenia later in life. Read More
A new study reports on the role a microRNA plays in major depressive disorder. Read More