Brain CancerFeaturedNeurologyOpen Neuroscience Articles·December 12, 2014·2 min read‘Trojan Horse’ Proteins Used to Target Hard to Reach CancersUsing nanoparticles, researchers have discovered a way to target difficult to reach cancers.Read More
FeaturedNeurologyOpen Neuroscience Articles·September 11, 2015·3 min readParkinson’s Disease Damaged Neurons Learn to Heal Themselves with Help of Modified White Blood CellsResearchers have genetically modified white blood cells to produce GDNF and deliver it to the brain, a new study reports.Read More
FeaturedNeurology·November 2, 2015·5 min readThe Innate Immune System Modulates the Severity of Multiple SclerosisA new study reports on the processes which amplify neuroinflammation in multiple sclerosis.Read More
FeaturedNeurology·October 13, 2015·3 min readBoosting the Brain’s Waste Disposal System to Help Fight Alzheimer’sResearchers investigate whether they can mobilize the immune system to help in the fight against Alzheimer's disease.Read More
FeaturedNeurologyNeurosciencePain·March 4, 2021·4 min readA New Cell Type Implicated in Chronic Pain and InflammationMRC1+ macrophages are dysfunctional in animal models of neuropathic pain. Stimulating the expression of the anti-inflammatory protein CD163 reduced signs of neuroinflammation in the spinal cords of mice with neuropathic pain.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·August 18, 2019·7 min readWhole body vibration shakes up microbiome, reducing inflammation in diabetesWhole-body vibration (WBV) therapy may be a way in which inflammation associated with diabetes can be controlled. WBV alters the microbiome, increasing levels of a bacterium that creates short-chain fatty acids, which help the body to better use glucose.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·March 16, 2020·2 min readA new strategy for the management of inflammatory painM2 macrophages can produce various endogenous opioids, such as endorphins, enkephalin, and dynorphin, which activate opioid receptors at the site of inflammation.Read More
FeaturedGenetics·January 6, 2016·6 min readRegeneration and Growth of Injured Peripheral Nerves Accelerated With Help of ProteinResearchers demonstrate the regenerative dynamics of CCL2.Read More
FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·August 21, 2018·4 min readHow the Body Clock Controls InflammationA new study sheds light on how the circadian clock controls inflammatory response. By understanding the link between inflammation and circadian rhythm, researchers believe it may be most effective to target specific conditions at certain times of the day. The findings may also explain why those who experience body clock disruptions are more susceptible to inflammatory conditions.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscience·June 10, 2019·5 min readStudy finds macrophages’ pathway to nurture PTEN-deficient glioblastoma: Mouse studyPTEN deficiency drives an increased expression of LOX. LOX attracts macrophages which protect gliobastoma brain cancer cells and provide growth factor support for the tumor, a new mouse study reveals.Read More
Brain CancerFeaturedNeurologyNeuroscience·June 25, 2019·4 min readScientists track brain tumor turncoats with advanced imagingAdvanced imaging techniques visualize macrophages in brain tumors in mouse models of glioblastoma.Read More
FeaturedGeneticsNeurology·December 5, 2017·5 min readInvestigating Protein’s Role in Lupus DevelopmentA new study reports the loss of the Bim protein in macrophages leads to lupus-like symptoms in mice. The findings may help in the development of new treatments for the autoimmune disease in humans.Read More