FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·November 24, 2021·3 min readNew Link Between a Disrupted Body Clock and Inflammatory DiseasesStudy identifies a significant way in which a disrupted circadian clock drives inflammation in the body's immune cells.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscience·June 10, 2019·5 min readStudy finds macrophages’ pathway to nurture PTEN-deficient glioblastoma: Mouse studyPTEN deficiency drives an increased expression of LOX. LOX attracts macrophages which protect gliobastoma brain cancer cells and provide growth factor support for the tumor, a new mouse study reveals.Read More
FeaturedGeneticsNeurology·March 17, 2016·4 min readImmune Cells Play Direct Role in Development of ALSImmune cells appear to play a direct role in the development of ALS, a new study reports.Read More
FeaturedNeurology·October 13, 2015·3 min readBoosting the Brain’s Waste Disposal System to Help Fight Alzheimer’sResearchers investigate whether they can mobilize the immune system to help in the fight against Alzheimer's disease.Read More
FeaturedGeneticsNeurology·December 5, 2017·5 min readInvestigating Protein’s Role in Lupus DevelopmentA new study reports the loss of the Bim protein in macrophages leads to lupus-like symptoms in mice. The findings may help in the development of new treatments for the autoimmune disease in humans.Read More
Brain CancerFeaturedNeurologyNeuroscience·June 25, 2019·4 min readScientists track brain tumor turncoats with advanced imagingAdvanced imaging techniques visualize macrophages in brain tumors in mouse models of glioblastoma.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·March 16, 2020·2 min readA new strategy for the management of inflammatory painM2 macrophages can produce various endogenous opioids, such as endorphins, enkephalin, and dynorphin, which activate opioid receptors at the site of inflammation.Read More
FeaturedNeurology·July 1, 2013·4 min readLack of Immune Cell Receptor Impairs Clearance of Amyloid Beta Protein from the BrainResearchers discover increased expression of the Scara1 protein could impede the progression of Alzheimer's disease as it plays an important role in the removal of amyloid beta from the brain.Read More
FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology·September 14, 2018·4 min readMore Immune Cells in Brains of Those with SchizophreniaA new study reports some people with schizophrenia have increased numbers of immune cells in their brains. Researchers say the immune cells may be producing inflammatory signals in those with the condition.Read More
FeaturedNeurologyNeurosciencePain·March 4, 2021·4 min readA New Cell Type Implicated in Chronic Pain and InflammationMRC1+ macrophages are dysfunctional in animal models of neuropathic pain. Stimulating the expression of the anti-inflammatory protein CD163 reduced signs of neuroinflammation in the spinal cords of mice with neuropathic pain.Read More
FeaturedNeurology·April 11, 2018·5 min readDiscovery Could Let Doctors Customize Brain’s Immune Response to DiseaseResearchers have discovered a method to engraft immune cells in the brains of lab mice without the use of radiation.Read More
FeaturedGeneticsNeurology·July 12, 2017·6 min readMissing Link Discovered Between Immune Cells and Alzheimer’s DiseaseResearchers at Cornell University have discovered a new pathway that involves immune cells which may contribute to the development of Alzheimer's disease.Read More
