PPCA treatment shown to provide therapeutic benefit in mouse models of hemophagocytic lymphohistiocytosis and multiple sclerosis.
The FDA has approved a new drug named Ozanimod for the treatment of multiple sclerosis. Ozanimod binds to receptors in lymphocytes' surfaces, preventing them from reaching the brain. As the number of active lymphocytes decreases, the attack on the immune system diminishes.
Researchers shed light on how a fever helps our immune systems fight infection. The study reports high temperature alters surface proteins of lymphocytes, making it easier for them to travel through blood vessels to reach infection sites.
Examining postmortem brains of ASD patients, researchers discover an accumulation of immune cells surrounding blood vessels in the brain. They also found blebs accumulating around blood vessels that contained astrocyte debris. The findings suggest autism may be an autoimmune disorder.
Researchers have discovered how TH1 and TH17 immune cells obtain access to neurons in multiple sclerosis.
A new study reports the loss of the Bim protein in macrophages leads to lupus-like symptoms in mice. The findings may help in the development of new treatments for the autoimmune disease in humans.
A new method is up to 92% accurate in predicting which patients with bipolar disorder will respond to lithium.
Noradrenaline impairs immune response by inhibiting the movement of leukocytes to different tissue.
Researchers found lymph-node-like structures close to glioma brain tumors in cancer patients. The study reveals immune cells within these structures can be activated to attack the brain tumor.
Persistent inflammation may underlie HIV associated neurocognitive disorders in patients taking specific antiretroviral drugs, a new study reports.
