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lymphatic system

·March 21, 2025·6 min read

Targeting Brain’s Drainage Pathways Rejuvenates Memory

Rejuvenating the brain's lymphatic vessels can enhance memory in aging mice by improving the removal of waste products from the brain. This research suggests that targeting the meningeal lymphatics—vessels outside the brain—could be a novel approach to treating age-related cognitive decline without directly crossing the blood-brain barrier.

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·July 13, 2024·5 min read

Brain’s Lymphatic System Plays Role in Migraine Pain

Researchers discovered how the protein CGRP affects the brain's lymphatic system, contributing to migraine pain. Their study reveals that CGRP prevents cerebrospinal fluid from draining, influencing migraine attacks. This finding could lead to new therapeutic strategies for migraines. More research is needed to understand the sex differences in migraine prevalence.

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·January 26, 2024·5 min read

Nasal Lymphatic Network Crucial for Brain CSF Drainage

Researchers discovered a crucial network of lymphatic vessels at the back of the nose, which significantly contributes to draining cerebrospinal fluid (CSF) from the brain. This study reveals a previously unknown CSF outflow route, offering insights into neurodegenerative conditions.

This shows a 3d map of the brain's drainage system

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·August 2, 2022·3 min read

The Brain’s Drainage System in 3D

The CSF drainage pathways are similar between mice and humans, researchers discovered.

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·October 18, 2021·4 min read

The Human Immune System Is an Early Riser

Activation of the immune system oscillates throughout the day, peaking just before we wake.

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·December 17, 2020·5 min read

Cellular Connections Found Between Nervous and Immune Systems

Researchers have identified a direct cellular interaction between the nervous system and the immune system. Pain sensing neurons around the lymph nodes can modulate lymph node activity.

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·September 16, 2019·4 min read

How lymphoma cells metastasize to the brain

In aging mice, chronic inflammatory processes lead lymphoma cells which entered the brain to be retained, rather than released directly back into the blood.

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·October 16, 2018·2 min read

Researchers Break New Ground in Understanding the Workings of the Lymphatic System

Researchers have identified the signaling molecules that activate the lymphatic pathway. The study also identified the cells that produce the signaling molecule and how they are used in lymphatic development.

Featured Neurology Neuroscience

·September 17, 2018·5 min read

Brain’s Lymphatic Vessels May Be New Treatment Avenue for Multiple Sclerosis

Researchers have discovered lymphatic vessels carry previously unknown messages from the brain to the immune system that triggers multiple sclerosis. Blocking the messages may provide new treatment options for the disease.

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·November 10, 2017·5 min read

Exit Through the Lymphatic System

A new study in Nature Communications refutes long standing belief, reporting that cerebrospinal fluid exits the cranial cavity via lymph vessels.

Image shows lymphatic vessels in the brain.

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·October 3, 2017·5 min read

‘Drain Pipes’ in the Brain: Lymphatic Vessels Act As Pipeline Between Brain and Immune System

A new study in eLife provides evidence that our brains may drain waste via our lymphatic vessels. The vessels may act as a 'pipeline' between the brain and immune system. Researchers say the findings could alter the way we think about how the brain and immune system inter-relate.

Featured Neurology Open Neuroscience Articles

·September 16, 2017·5 min read

Tattoos Are More Than Skin Deep: Ink Can Reach Lymph Nodes

A new study reveals nanoparticles from tattoo ink travels into the body and reaches the lymph nodes. Researchers have collected visual evidence showing lymph nodes tinted with the colors of a person's tattoos.