Researchers report LSD triggers a reduction in functional connection between areas of the brain that govern cognitive processes, while increasing connectivity in brain networks associated with sensory functions.
A new study reports those who microdose psychedelics report improvements in attention and mental health. However, a number of people report an increase in neuroticism following six weeks of microdosing.
Microdosing, a growing trend where people take small doses for psychedelic drugs, is associated with improved mood, focus, and creativity. For some, microdosing may provide a possible alternative to SSRI antidepressants. However, researchers warn of some potential problems with microdosing, including negative side effects, psychological stigma, and exposure to elicit, black market products.
While many people report microdosing is beneficial to their mental wellbeing, researchers say more research needs to be conducted to evaluate the psychological and health implications of taking low-dose psychedelics.
Those who microdose psychedelics report improved mood, greater focus, and increased creativity. A new study looks at the positive outcomes of microdosing and suggests others look at potential long-term negative consequences of using psychedelics.
Numerous studies have linked controlled psychedelics to improvements in mental health conditions such as depression and PTSD. In March, the FDA approved Esketamine as a treatment for depression. However, with much stigma surrounding psychedelics, researchers question how many patients would take psychedelic medications if prescribed to them. According to a new study, 40% of people with no experience of psychedelics would be unlikely to take the prescription due to fears of 'brain damage' or a 'bad trip'.
DMT alters electrical activity in the brain. The compound significantly decreases alpha wave activity, the dominant rhythm associated with wakefulness, and increases theta waves, associated with dreaming. Overall brain activity becomes more chaotic and less predictable. The findings advance the understanding of the neurobiological underpinnings of immersive states of consciousness.
Study discussed the benefits of using psychedelics as an antidepressant option for those with depression.
A recent case study report highlights the effects of LSD overdoses on three women, revealing the subjects experienced improvements in physical and mental health following their overdoses.
Psilocybin reduces activity in the claustrum, an area of the brain believed to contribute to consciousness and sense of self. Researchers say the reduced activity may tie in with the reduced sense of self and ego often associated with psychedelic drug use. The study also reports psilocybin alters the way the claustrum communicates with brain areas involved in attention, decision making, auditory processing, and memory.
Researchers have uncovered the structure of psychedelic compounds when they actively bind to the 5-HT2A serotonin receptor on the surface of brain cells. The discovery could lead to the exploration of more precise compounds that offer the therapeutic effects of psychedelics for mental health disorders, but without the hallucinations.