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longevity

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Featured Neuroscience Open Neuroscience Articles

·July 28, 2020·4 min read

Pessimistic Outlook on Life Linked to Life Expectancy

Pessimistic people are more likely to die earlier from cardiovascular disease and other causes, but not from cancer than those who have a more optimistic outlook on life. However, optimists did not have a greater than average life expectancy.

Featured Genetics Neuroscience

·January 12, 2024·6 min read

Eat Less, Live Longer: Dietary Restrictions Increase Lifespan and Improve Brain Health

Recent research reveals a significant discovery about dietary restriction and its impact on brain health and aging. They identified the OXR1 gene as crucial for extending lifespan and ensuring healthy brain aging, particularly in response to dietary restriction.

Featured Neuroscience

·February 23, 2023·5 min read

Getting Good Sleep Could Add Years to Your Life

Findings suggest up to 8% of deaths by any cause could be attributed to poor sleep patterns. Researchers say those who have healthier sleep habits are incrementally less likely to die early.

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Featured Neuroscience

·January 9, 2023·5 min read

Variety of Healthy Eating Patterns Linked With Lower Risk of Premature Death

Following at least one of four healthy eating patterns reduces the risk of death as a result of cardiovascular disease, cancer, or respiratory disease.

Featured Genetics Neuroscience

·May 19, 2025·6 min read

Want to Live to 115? Here’s What Research Says You Should Do

New insights from longevity research suggest that lifestyle—not just genetics—plays a vital role in living a longer, healthier life. While rare individuals like 115-year-old Ethel Caterham may benefit from exceptional genes, research shows that physical activity, diet, sleep, and stress management are key factors that can significantly influence lifespan.

Featured Genetics Neuroscience

·July 27, 2022·7 min read

Biological Age, Not Birthdate May Reveal Healthy Longevity

Accelerated biological and epigenetic aging was associated with lower odds of older women living to the age of 90 and beyond.

Featured Neuroscience

·October 10, 2024·6 min read

Study Links Calorie Restriction to Longevity

A new study found that calorie restriction, rather than intermittent fasting, had the greatest impact on extending lifespan in mice. Surprisingly, the mice that lived the longest maintained stable body weight and energy levels despite eating less, while those that lost significant weight had shorter lifespans. The findings indicate that genetic factors and resilience to stress play crucial roles in how dietary changes impact health and longevity.

Featured Genetics Neurology Neuroscience

·May 13, 2026·8 min read

APOE2 Protects Neurons from DNA Damage and Aging

Researchers discovered that the APOE2 gene variant shields the brain by helping neurons repair DNA damage and resist cellular senescence. By shifting focus from lipid transport to genomic integrity, this study identifies a new biological mechanism for longevity and suggests that mimicking APOE2's effects could lead to breakthrough treatments for Alzheimer’s disease.

Featured Genetics Open Neuroscience Articles

·December 2, 2015·6 min read

Fountain of Youth: Tweaking Genes to Extend Lifespan

Researchers have identified genes implicated in physical aging and discovered that influencing just one of the genes can extend the healthy lifespan of animals.

Featured Neuroscience Psychology

·November 16, 2024·3 min read

How Depression Alters Stress, Health, and Lifespan

Depression disrupts the body's stress systems, causing physical health risks like heart disease, diabetes, and stroke, and reducing life expectancy by 7-10 years. The condition triggers brain structure changes, such as a 40% reduction in subgenual prefrontal cortex volume, and disrupts hormone systems involving CRH, norepinephrine, and cortisol.

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·October 8, 2019·8 min read

Dog ownership associated with longer life, especially among heart attack and stroke survivors

Owning a dog was associated with a 33% lower risk of death for heart attack survivors who lived alone, and a 27% reduced risk for those who suffered a stroke, compared to those who did not own a pet. Additionally, dog ownership was linked to a 24% reduced risk of all-cause mortality and a 31% reduced risk of death by heart attack or stroke.

Featured Genetics Neuroscience Open Neuroscience Articles

·September 7, 2017·5 min read

Researchers Slow Aging and Extend Lifespan of Fruit Flies

Researchers have developed a method of removing damaged mitochondria in fruit flies, causing the insects to become more active and increasing typical lifespan. UCLA researchers report the method could eventually be used to benefit humans and delay the onset of age-related diseases.