A new study reports the locus coeruleus, an area of the brain essential for maintaining cognitive function, is vulnerable to toxins and infections. This brain area appears to be the first place affected by late onset Alzheimer's.
Tau accumulations disrupt wake-promoting neurons. The findings help explain why day-time napping and sleep disruptions are often reported in Alzheimer's patients.
A new mouse study reveals females have a three fold higher abundance of EP3, in addition to elevated levels of genes associated with major depressive disorder in the locus coeruleus.
Exercise increases levels of galanin in the brain stem, making mice more resilient to stress.
Those on the autism spectrum had atypically smaller pupil dilation compared to the control group during distracting conditions while taking a push-button test. The findings suggest those with ASD may have dysregulation in locus coeruleus activity. The dysregulation of the LC may explain the exaggerated responses to environmental stimuli and fixated behaviors many with ASD experience.
Study sheds light on the brain chemistry involved in attention loss when a person drinks alcohol.
According to a new study, brief exposure to mild trauma or sudden sounds can permanently alter neural networks and form long lasting memories.
Adults with mild cognitive impairment (MCI), a precursor to Alzheimer's disease, have greater pupil dilation when taking cognitive tests than their cognitively normal peers. Task-evoked pupillary response may be a cost-effective, and low invasive screening test for those at genetic risk for Alzheimer's before the symptoms of the disease take hold.
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RIKEN researchers report neurons in the locus coeruleus play a key role in emotional and flexible learning.