Researchers have implicated an enzyme that appears to make both Tau and alpha synculein more toxic in Alzheimer's and Parkinson's disease. Inhibiting this enzyme has already proved helpful in treating animal models of Alzheimer's disease. The researchers report they are moving on to testing drugs that inhibit AEP in animal models of Parkinson's disease.
Researchers report those who have had appendectomies have a reduced risk of developing Parkinson's disease. A new study reveals the appendix acts as a reservoir for proteins associated with the neurodegenerative disease.
Researchers have created an artificial enzyme that stops alpha-synuclein from spreading. The findings could have positive implications for the treatment of Parkinson's disease.
Hippocampal shrinkage may could signify people with memory problems could develop Lewy body dementia rather than Alzheimer's disease, a new study reports.
A new method of examining blood plasma allowed researchers to identify specific chemical bonds within the blood. The new technique allowed researchers to accurately distinguish between Alzheimer's disease and Lewy body dementia, thus reducing cases of misdiagnosis.
Using a tiny dose of the leukemia drug nilotinib, researchers halt the accumulation of toxic proteins linked to Parkinson's diseases in the brains of mice.
Researchers report dream dysfunctions and sleep disorders may be warning signs of neurodegenerative diseases up to 15 years before other symptoms appear.
Study identified five genes, including two novel genes, associated with Lewy Body dementia. Researchers also found the genetic profiles of patients with LBD showed higher chances of also suffering from Alzheimer's and Parkinson's disease than other age-matched control subjects.
Combining PET neuroimaging with a specific intravenous radioactive compound allows researchers to distinguish Lewy Body Dementia from Parkinson's disease and Alzheimer's in brain scans.
Increased ceramide levels in the brain may be a unique feature of all types of Lewy body dementias, including LBD associated with Parkinson's disease.
Researchers have identified key risk factors for a violent sleep disorder known as REM sleep behavior disorder. According to the study, taking antidepressants, having PTSD and anxiety disorders increases the risk for violent episodes during sleep.
Researchers detail the complex interaction between alpha synuclein and the prion protein PrPc.